Eva Wrobel

Bochum, NW 44801, Germany

Last Updated: 09/26/2026

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Found 11 publications

KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures.

KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: June 10, 2024

A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling.

A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling.

Journal: Communications biology

Published: September 04, 2020

Structural interplay of KV7.1 and KCNE1 is essential for normal repolarization and is compromised in short QT syndrome 2 (KV7.1-A287T).

Structural interplay of KV7.1 and KCNE1 is essential for normal repolarization and is compromised in short QT syndrome 2 (KV7.1-A287T).

Journal: HeartRhythm case reports

Published: May 12, 2017

The Natural Plant Product Rottlerin Activates Kv7.1/KCNE1 Channels.

The Natural Plant Product Rottlerin Activates Kv7.1/KCNE1 Channels.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Published: November 30, 2016

In Vitro Analyses of Novel HCN4 Gene Mutations.

In Vitro Analyses of Novel HCN4 Gene Mutations.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Published: October 11, 2016

KCNE1 induces fenestration in the Kv7.1/KCNE1 channel complex that allows for highly specific pharmacological targeting.

KCNE1 induces fenestration in the Kv7.1/KCNE1 channel complex that allows for highly specific pharmacological targeting.

Journal: Nature communications

Published: May 28, 2015

Klotho: a new trafficking modifier of Kv7.1/KCNE1 channels.

Klotho: a new trafficking modifier of Kv7.1/KCNE1 channels.

Journal: Channels (Austin, Tex.)

Published: December 06, 2014

Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.

Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 03, 2014

Novel Kv7.1-phosphatidylinositol 4,5-bisphosphate interaction sites uncovered by charge neutralization scanning.

Novel Kv7.1-phosphatidylinositol 4,5-bisphosphate interaction sites uncovered by charge neutralization scanning.

Journal: The Journal of biological chemistry

Published: June 21, 2014

Structural basis of PI(4,5)P2-dependent regulation of GluA1 by phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP5K2A).

Structural basis of PI(4,5)P2-dependent regulation of GluA1 by phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP5K2A).

Journal: Pflugers Archiv : European journal of physiology

Published: July 10, 2013

The KCNE Tango - How KCNE1 Interacts with Kv7.1.

The KCNE Tango - How KCNE1 Interacts with Kv7.1.

Journal: Frontiers in pharmacology

Published: March 29, 2012

Showing 1-11 of 11

Last Updated: 09/26/2026