Evelyn Houtman

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 13 publications

Development of Reliable and High-Throughput Human Biomimetic Cartilage and Bone Models to Explore Senescence and Personalized Osteoarthritis Treatment Options.

Development of Reliable and High-Throughput Human Biomimetic Cartilage and Bone Models to Explore Senescence and Personalized Osteoarthritis Treatment Options.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Published: October 30, 2024

Exploring the therapeutic effect of human recombinant IL11 on lesioned OA human osteochondral explants.

Exploring the therapeutic effect of human recombinant IL11 on lesioned OA human osteochondral explants.

Journal: Arthritis research & therapy

Published: May 07, 2024

Thyroid hormone induces ossification and terminal maturation in a preserved OA cartilage biomimetic model.

Thyroid hormone induces ossification and terminal maturation in a preserved OA cartilage biomimetic model.

Journal: Arthritis research & therapy

Published: October 29, 2023

WWP2 confers risk to osteoarthritis by affecting cartilage matrix deposition via hypoxia associated genes.

WWP2 confers risk to osteoarthritis by affecting cartilage matrix deposition via hypoxia associated genes.

Journal: Osteoarthritis and cartilage

Published: June 29, 2022

Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes.

Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes.

Journal: Rheumatology (Oxford, England)

Published: October 20, 2021

Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants.

Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants.

Journal: Arthritis research & therapy

Published: June 15, 2021

Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling.

Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling.

Journal: BMC medicine

Published: May 12, 2021

Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis.

Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis.

Journal: Rheumatology and therapy

Published: December 07, 2020

Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K inhibitor warfarin.

Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K inhibitor warfarin.

Journal: Osteoarthritis and cartilage

Published: November 25, 2020

RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets.

RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets.

Journal: Arthritis & rheumatology (Hoboken, N.J.)

Published: June 04, 2020

Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration.

Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration.

Journal: Rheumatology (Oxford, England)

Published: December 06, 2019

RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage.

RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage.

Journal: Annals of the rheumatic diseases

Published: June 06, 2018

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Last Updated: 09/26/2026