Evi Kostenis

Bonn, NW 53127, Germany

Last Updated: 09/26/2026

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Found 129 publications

Beta arrestin 1 is a key regulator of pulmonary vascular tone.

Beta arrestin 1 is a key regulator of pulmonary vascular tone.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: February 09, 2026

Brain endothelial Gαq/11 signalling in cerebrovascular function and cognition of aged mice.

Brain endothelial Gαq/11 signalling in cerebrovascular function and cognition of aged mice.

Journal: EBioMedicine
Published: September 17, 2025

Targeting of specific CCR5-G protein complexes underlies biased signaling by HIV-1 envelope glycoproteins.

Targeting of specific CCR5-G protein complexes underlies biased signaling by HIV-1 envelope glycoproteins.

Journal: Cell communication and signaling : CCS
Published: August 04, 2025

Cyclic peptide inhibitors function as molecular glues to stabilize Gq/11 heterotrimers.

Cyclic peptide inhibitors function as molecular glues to stabilize Gq/11 heterotrimers.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: May 07, 2025

Identification of a regulatory sequence within the third intracellular loop that governs β-arrestin binding to the muscarinic M5 receptor.

Identification of a regulatory sequence within the third intracellular loop that governs β-arrestin binding to the muscarinic M5 receptor.

Journal: Cellular signalling
Published: April 23, 2025

An integrated mechanism of Gq regulation of PLCβ enzymes.

An integrated mechanism of Gq regulation of PLCβ enzymes.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: April 18, 2025

GPR17 - orphan G protein-coupled receptor with therapeutic potential.

GPR17 - orphan G protein-coupled receptor with therapeutic potential.

Journal: Trends in pharmacological sciences
Published: March 24, 2025

A Fluorescent Probe Enables the Discovery of Improved Antagonists Targeting the Intracellular Allosteric Site of the Chemokine Receptor CCR7.

A Fluorescent Probe Enables the Discovery of Improved Antagonists Targeting the Intracellular Allosteric Site of the Chemokine Receptor CCR7.

Journal: Journal of medicinal chemistry
Published: February 12, 2025

Discovery of Anthranilic Acid Derivatives as Antagonists of the Pro-Inflammatory Orphan G Protein-Coupled Receptor GPR17.

Discovery of Anthranilic Acid Derivatives as Antagonists of the Pro-Inflammatory Orphan G Protein-Coupled Receptor GPR17.

Journal: Journal of medicinal chemistry
Published: November 01, 2024

Psychedelic compounds directly excite 5-HT2A layer V medial prefrontal cortex neurons through 5-HT2A Gq activation.

Psychedelic compounds directly excite 5-HT2A layer V medial prefrontal cortex neurons through 5-HT2A Gq activation.

Journal: Translational psychiatry
Published: August 15, 2024

G protein-mediated signal transduction: a molecular choreography of G protein activation after GTP binding.

G protein-mediated signal transduction: a molecular choreography of G protein activation after GTP binding.

Journal: Signal transduction and targeted therapy
Published: May 06, 2024

Development of a NanoBRET Assay Platform to Detect Intracellular Ligands for the Chemokine Receptors CCR6 and CXCR1.

Development of a NanoBRET Assay Platform to Detect Intracellular Ligands for the Chemokine Receptors CCR6 and CXCR1.

Journal: ChemMedChem
Published: April 19, 2024
Showing 1-12 of 129

Last Updated: 09/26/2026