Ewgenij Proschak

Max Von Laue Str. 9
Frankfurt Am Main, HE 60438, Germany

Last Updated: 09/26/2026

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Found 138 publications

First Structure-Activity-Relationship Study of Potent G2A Antagonists.

First Structure-Activity-Relationship Study of Potent G2A Antagonists.

Journal: Journal of medicinal chemistry

Published: June 11, 2026

Fragment-Based Discovery of Fenamic Acids as Pan-Species Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain.

Fragment-Based Discovery of Fenamic Acids as Pan-Species Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain.

Journal: ACS chemical biology

Published: May 25, 2026

Structure Merging Approach Leads to New Dual Potent and Selective USP25/USP28 Inhibitors.

Structure Merging Approach Leads to New Dual Potent and Selective USP25/USP28 Inhibitors.

Journal: Journal of medicinal chemistry

Published: April 22, 2026

Improved Total Synthesis of Cannabioxepane, a Minor Phytocannabinoid from Cannabis sativa L.

Improved Total Synthesis of Cannabioxepane, a Minor Phytocannabinoid from Cannabis sativa L.

Journal: Organic letters

Published: March 18, 2026

Click. Screen. Degrade. A Miniaturized D2B Workflow for Rapid PROTAC Discovery.

Click. Screen. Degrade. A Miniaturized D2B Workflow for Rapid PROTAC Discovery.

Journal: Journal of medicinal chemistry

Published: January 23, 2026

Exploiting the 2-(1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic Acid Scaffold to Generate COXTRANs: A New Class of Dual Cyclooxygenase Inhibitors-Thromboxane Receptor Antagonists.

Exploiting the 2-(1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic Acid Scaffold to Generate COXTRANs: A New Class of Dual Cyclooxygenase Inhibitors-Thromboxane Receptor Antagonists.

Journal: Journal of medicinal chemistry

Published: October 22, 2025

Click chemistry enables rapid development of potent sEH PROTACs using a direct-to-biology approach.

Click chemistry enables rapid development of potent sEH PROTACs using a direct-to-biology approach.

Journal: Chemical communications (Cambridge, England)

Published: October 21, 2025

Development of Potent and Selective Dual PPARδ/sEH Modulators from an AI-Designed Scaffold.

Development of Potent and Selective Dual PPARδ/sEH Modulators from an AI-Designed Scaffold.

Journal: Journal of medicinal chemistry

Published: September 18, 2025

Inactivation of the Phosphatase Activity of Soluble Epoxide Hydrolase Modulates SIRT3 and Attenuates Experimental Pulmonary Hypertension.

Inactivation of the Phosphatase Activity of Soluble Epoxide Hydrolase Modulates SIRT3 and Attenuates Experimental Pulmonary Hypertension.

Journal: Comprehensive Physiology

Published: August 16, 2025

Sustainable Joullié-Ugi and Continuous Flow Implementation Led to Novel Captopril-Inspired Broad-Spectrum Metallo-β-Lactamase Inhibitors.

Sustainable Joullié-Ugi and Continuous Flow Implementation Led to Novel Captopril-Inspired Broad-Spectrum Metallo-β-Lactamase Inhibitors.

Journal: Journal of medicinal chemistry

Published: August 15, 2025

Structure-Based Design of PROTACS for the Degradation of Soluble Epoxide Hydrolase.

Structure-Based Design of PROTACS for the Degradation of Soluble Epoxide Hydrolase.

Journal: Journal of medicinal chemistry

Published: June 18, 2025

Rediscovering nitroxoline: a metal-chelating agent bridging infection and cancer.

Rediscovering nitroxoline: a metal-chelating agent bridging infection and cancer.

Journal: Drug discovery today

Published: May 22, 2025

Showing 1-12 of 138

Last Updated: 09/26/2026