Fabian Kasermann

Bern, BE 3010, Switzerland

Last Updated: 09/26/2026

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Found 30 publications

Engineered Trivalent Human IgG1-Fc Proteins for Potent Complement Inhibition.

Engineered Trivalent Human IgG1-Fc Proteins for Potent Complement Inhibition.

Journal: Cells
Published: April 30, 2026

Recombinant Human IgG1-Hexamer Reduces Pathogenic Autoantibodies in the K/BxN Mouse Model of Arthritis Independent of FcRn.

Recombinant Human IgG1-Hexamer Reduces Pathogenic Autoantibodies in the K/BxN Mouse Model of Arthritis Independent of FcRn.

Journal: International journal of molecular sciences
Published: December 22, 2025

Recombinant IgG1 Fc-μTP-L309C Ameliorates Endogenous Rheumatoid Arthritis in the K/BxN Mouse Model by Decreasing Th1 and Th17 Cells in the Spleen, Lymph Nodes and Joint and Increasing T Regulatory Cells and IL-10 in the Joint.

Recombinant IgG1 Fc-μTP-L309C Ameliorates Endogenous Rheumatoid Arthritis in the K/BxN Mouse Model by Decreasing Th1 and Th17 Cells in the Spleen, Lymph Nodes and Joint and Increasing T Regulatory Cells and IL-10 in the Joint.

Journal: Journal of clinical medicine
Published: May 22, 2025

Regulation of immune cell metabolism by therapeutic normal IgG intravenous immunoglobulin.

Regulation of immune cell metabolism by therapeutic normal IgG intravenous immunoglobulin.

Journal: The Journal of allergy and clinical immunology
Published: December 02, 2024

Intravenous immunoglobulin (IVIG) promotes brain repair and improves cognitive outcomes after traumatic brain injury in a FcγRIIB receptor-dependent manner.

Intravenous immunoglobulin (IVIG) promotes brain repair and improves cognitive outcomes after traumatic brain injury in a FcγRIIB receptor-dependent manner.

Journal: Brain, behavior, and immunity
Published: August 19, 2022

Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis.

Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis.

Journal: Pharmacology
Published: August 16, 2022

Mechanism of increased efficacy of recombinant Fc-μTP-L309C compared to IVIg to ameliorate mouse immune thrombocytopenia.

Mechanism of increased efficacy of recombinant Fc-μTP-L309C compared to IVIg to ameliorate mouse immune thrombocytopenia.

Journal: EJHaem
Published: August 10, 2021

High Dose Intravenous IgG Therapy Modulates Multiple NK Cell and T Cell Functions in Patients With Immune Dysregulation.

High Dose Intravenous IgG Therapy Modulates Multiple NK Cell and T Cell Functions in Patients With Immune Dysregulation.

Journal: Frontiers in immunology
Published: January 29, 2021

Therapeutic normal IgG intravenous immunoglobulin activates Wnt-β-catenin pathway in dendritic cells.

Therapeutic normal IgG intravenous immunoglobulin activates Wnt-β-catenin pathway in dendritic cells.

Journal: Communications biology
Published: October 10, 2019

Intravenous immunoglobulin mediates anti-inflammatory effects in peripheral blood mononuclear cells by inducing autophagy.

Intravenous immunoglobulin mediates anti-inflammatory effects in peripheral blood mononuclear cells by inducing autophagy.

Journal: Cell death & disease
Published: September 26, 2019

Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-μTP-L309C, a recombinant IgG1 Fc hexamer.

Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-μTP-L309C, a recombinant IgG1 Fc hexamer.

Journal: BMC immunology
Published: July 21, 2019

Next-generation Fc receptor-targeting biologics for autoimmune diseases.

Next-generation Fc receptor-targeting biologics for autoimmune diseases.

Journal: Autoimmunity reviews
Published: April 07, 2019
Showing 1-12 of 30

Last Updated: 09/26/2026