Fabio D. Di Domenico

Rome, Italy

Last Updated: 09/26/2026

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Found 99 publications

BACH1/HO-1 Axis Dysregulation Links Down Syndrome to Alzheimer-like Neurodegeneration.

BACH1/HO-1 Axis Dysregulation Links Down Syndrome to Alzheimer-like Neurodegeneration.

Journal: Neurochemistry international

Published: May 05, 2026

Promoting Research Excellence in Down Syndrome: Proceedings of the 5th International Conference of the Trisomy 21 Research Society.

Promoting Research Excellence in Down Syndrome: Proceedings of the 5th International Conference of the Trisomy 21 Research Society.

Journal: Neuromolecular medicine

Published: March 13, 2026

Loss of Proteostasis and Early-Onset Neurodegeneration in Down Syndrome: From Mechanisms to Interventions.

Loss of Proteostasis and Early-Onset Neurodegeneration in Down Syndrome: From Mechanisms to Interventions.

Journal: Antioxidants (Basel, Switzerland)

Published: March 13, 2026

HMC3 revealed: how much do these "Microglia" really tell us?

HMC3 revealed: how much do these "Microglia" really tell us?

Journal: Frontiers in immunology

Published: December 31, 2025

Systemic administration of the OGT inhibitor OSMI-1 normalizes hippocampal O-GlcNAcylation and improves recognition memory, redox balance, and brain mitochondrial homeostasis in a Rett syndrome mouse model.

Systemic administration of the OGT inhibitor OSMI-1 normalizes hippocampal O-GlcNAcylation and improves recognition memory, redox balance, and brain mitochondrial homeostasis in a Rett syndrome mouse model.

Journal: Free radical biology & medicine

Published: November 18, 2025

Age-related behavioral and molecular landmarks in new mouse models for studying Alzheimer's disease in Down syndrome.

Age-related behavioral and molecular landmarks in new mouse models for studying Alzheimer's disease in Down syndrome.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: October 28, 2025

GDF-11, GDF-15, Jag-1, and leptin in neuronal-derived extracellular vesicles as aging-related biomarkers to identify individuals at risk of Alzheimer's dementia: A pilot study.

GDF-11, GDF-15, Jag-1, and leptin in neuronal-derived extracellular vesicles as aging-related biomarkers to identify individuals at risk of Alzheimer's dementia: A pilot study.

Journal: Neurobiology of disease

Published: October 13, 2025

Biliverdin reductase-A is a key modulator in insulin signaling and metabolism.

Biliverdin reductase-A is a key modulator in insulin signaling and metabolism.

Journal: Trends in endocrinology and metabolism: TEM

Published: July 17, 2025

Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers.

Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers.

Journal: Redox biology

Published: May 15, 2025

Corrigendum to "Altered mitochondrial unfolded protein response and protein quality control promote oxidative distress in down syndrome brain" [Free Radic. Biol. Med. 227 (2025) 80-93].

Corrigendum to "Altered mitochondrial unfolded protein response and protein quality control promote oxidative distress in down syndrome brain" [Free Radic. Biol. Med. 227 (2025) 80-93].

Journal: Free radical biology & medicine

Published: May 06, 2025

Proteome Signature of Alzheimer-Like Phenotypes in Frontal Cortices From Young and Old Individuals With Down Syndrome.

Proteome Signature of Alzheimer-Like Phenotypes in Frontal Cortices From Young and Old Individuals With Down Syndrome.

Journal: Molecular neurobiology

Published: April 30, 2025

Proteostasis Decline and Redox Imbalance in Age-Related Diseases: The Therapeutic Potential of NRF2.

Proteostasis Decline and Redox Imbalance in Age-Related Diseases: The Therapeutic Potential of NRF2.

Journal: Biomolecules

Published: November 26, 2024

Showing 1-12 of 99

Last Updated: 09/26/2026