Fabrice Gouilleux

INSERM UMR 1100 CEPR, Team 2, 10 Boulevard Tonnellé
Tours, 37032, France

Last Updated: 09/26/2026

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Found 29 publications

Novel antileukemic compound with sub-micromolar potency against STAT5 addicted myeloid leukemia cells.

Novel antileukemic compound with sub-micromolar potency against STAT5 addicted myeloid leukemia cells.

Journal: European journal of medicinal chemistry
Published: November 14, 2024

Targeted Therapeutic Strategies for the Treatment of Cancer.

Targeted Therapeutic Strategies for the Treatment of Cancer.

Journal: Cancers
Published: January 03, 2024

Diphenyleneiodonium Triggers Cell Death of Acute Myeloid Leukemia Cells by Blocking the Mitochondrial Respiratory Chain, and Synergizes with Cytarabine.

Diphenyleneiodonium Triggers Cell Death of Acute Myeloid Leukemia Cells by Blocking the Mitochondrial Respiratory Chain, and Synergizes with Cytarabine.

Journal: Cancers
Published: December 07, 2021

Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases.

Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases.

Journal: Molecules (Basel, Switzerland)
Published: October 04, 2021

Characterization of NADPH Oxidase Expression and Activity in Acute Myeloid Leukemia Cell Lines: A Correlation with the Differentiation Status.

Characterization of NADPH Oxidase Expression and Activity in Acute Myeloid Leukemia Cell Lines: A Correlation with the Differentiation Status.

Journal: Antioxidants (Basel, Switzerland)
Published: February 07, 2021

New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation.

New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation.

Journal: Molecules (Basel, Switzerland)
Published: January 07, 2021

Design, synthesis, and antiproliferative effect of 2,9-bis[4-(pyridinylalkylaminomethyl)phenyl]-1,10-phenanthroline derivatives on human leukemic cells by targeting G-quadruplex.

Design, synthesis, and antiproliferative effect of 2,9-bis[4-(pyridinylalkylaminomethyl)phenyl]-1,10-phenanthroline derivatives on human leukemic cells by targeting G-quadruplex.

Journal: Archiv der Pharmazie
Published: December 01, 2020

Inhibitors Targeting STAT5 Signaling in Myeloid Leukemias: New Tetrahydroquinoline Derivatives with Improved Antileukemic Potential.

Inhibitors Targeting STAT5 Signaling in Myeloid Leukemias: New Tetrahydroquinoline Derivatives with Improved Antileukemic Potential.

Journal: ChemMedChem
Published: October 16, 2020

VAS3947 Induces UPR-Mediated Apoptosis through Cysteine Thiol Alkylation in AML Cell Lines.

VAS3947 Induces UPR-Mediated Apoptosis through Cysteine Thiol Alkylation in AML Cell Lines.

Journal: International journal of molecular sciences
Published: July 01, 2020

Repurposing of Acriflavine to Target Chronic Myeloid Leukemia Treatment.

Repurposing of Acriflavine to Target Chronic Myeloid Leukemia Treatment.

Journal: Current medicinal chemistry
Published: May 28, 2020

Horizontal meta-analysis identifies common deregulated genes across AML subgroups providing a robust prognostic signature.

Horizontal meta-analysis identifies common deregulated genes across AML subgroups providing a robust prognostic signature.

Journal: Blood advances
Published: April 13, 2020

STAT5 is Expressed in CD34+/CD38- Stem Cells and Serves as a Potential Molecular Target in Ph-Negative Myeloproliferative Neoplasms.

STAT5 is Expressed in CD34+/CD38- Stem Cells and Serves as a Potential Molecular Target in Ph-Negative Myeloproliferative Neoplasms.

Journal: Cancers
Published: April 03, 2020
Showing 1-12 of 29

Last Updated: 09/26/2026