Fadi Rofo
Uppsala, C 75123, Sweden
Last Updated: 09/26/2026
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Found 12 publications
Somatostatin therapy, neprilysin activation, and amyloid beta reduction: A novel approach for Alzheimer's treatment.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: April 15, 2025
A shorter linker in the bispecific antibody RmAb158-scFv8D3 improves TfR-mediated blood-brain barrier transcytosis in vitro.
Journal: Scientific reports
Published: August 12, 2024
Standardized Preclinical In Vitro Blood-Brain Barrier Mouse Assay Validates Endocytosis-Dependent Antibody Transcytosis Using Transferrin-Receptor-Mediated Pathways.
Journal: Molecular pharmaceutics
Published: February 22, 2023
Introducing or removing heparan sulfate binding sites does not alter brain uptake of the blood-brain barrier shuttle scFv8D3.
Journal: Scientific reports
Published: October 14, 2022
A Brain-Targeting Bispecific-Multivalent Antibody Clears Soluble Amyloid-Beta Aggregates in Alzheimer's Disease Mice.
Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Published: July 20, 2022
Blood-brain barrier penetrating neprilysin degrades monomeric amyloid-beta in a mouse model of Alzheimer's disease.
Journal: Alzheimer's research & therapy
Published: July 13, 2022
A single-chain fragment constant design enables easy production of a monovalent blood-brain barrier transporter and provides an improved brain uptake at elevated doses.
Journal: Journal of neurochemistry
Published: July 08, 2022
Wide-Ranging Effects on the Brain Proteome in a Transgenic Mouse Model of Alzheimer's Disease Following Treatment with a Brain-Targeting Somatostatin Peptide.
Journal: ACS chemical neuroscience
Published: June 25, 2021
Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta.
Journal: Translational neurodegeneration
Published: March 17, 2021
Characterization of Dmrt3-Derived Neurons Suggest a Role within Locomotor Circuits.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience
Published: January 31, 2018
Showing 1-12 of 12
Last Updated: 09/26/2026