Fangchao Bi

Key Laboratory Of Chemical Biology, 44 West Wenhua Road
Jinan, 250012, China

Last Updated: 09/26/2026

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Found 11 publications

Design, synthesis and antibacterial evaluation of novel C-11, C-9 or C-2'-substituted 3-O-descladinosyl-3-ketoclarithromycin derivatives.

Design, synthesis and antibacterial evaluation of novel C-11, C-9 or C-2'-substituted 3-O-descladinosyl-3-ketoclarithromycin derivatives.

Journal: Bioorganic & medicinal chemistry letters

Published: February 10, 2021

Antimicrobial Action and Reversal of Resistance in MRSA by Difluorobenzamide Derivatives Targeted at FtsZ.

Antimicrobial Action and Reversal of Resistance in MRSA by Difluorobenzamide Derivatives Targeted at FtsZ.

Journal: Antibiotics (Basel, Switzerland)

Published: October 16, 2020

Design, synthesis of novel 4,5-dihydroisoxazole-containing benzamide derivatives as highly potent FtsZ inhibitors capable of killing a variety of MDR Staphylococcus aureus.

Design, synthesis of novel 4,5-dihydroisoxazole-containing benzamide derivatives as highly potent FtsZ inhibitors capable of killing a variety of MDR Staphylococcus aureus.

Journal: Bioorganic & medicinal chemistry

Published: June 03, 2020

Design, synthesis and antibacterial evaluation of novel 15-membered 11a-azahomoclarithromycin derivatives with the 1, 2, 3-triazole side chain.

Design, synthesis and antibacterial evaluation of novel 15-membered 11a-azahomoclarithromycin derivatives with the 1, 2, 3-triazole side chain.

Journal: European journal of medicinal chemistry

Published: April 09, 2019

Discovery of 1,3,4-oxadiazol-2-one-containing benzamide derivatives targeting FtsZ as highly potent agents of killing a variety of MDR bacteria strains.

Discovery of 1,3,4-oxadiazol-2-one-containing benzamide derivatives targeting FtsZ as highly potent agents of killing a variety of MDR bacteria strains.

Journal: Bioorganic & medicinal chemistry

Published: March 06, 2019

Design, synthesis and structure-based optimization of novel isoxazole-containing benzamide derivatives as FtsZ modulators.

Design, synthesis and structure-based optimization of novel isoxazole-containing benzamide derivatives as FtsZ modulators.

Journal: European journal of medicinal chemistry

Published: July 15, 2018

Novel 5-methyl-2-phenylphenanthridium derivatives as FtsZ-targeting antibacterial agents from structural simplification of natural product sanguinarine.

Novel 5-methyl-2-phenylphenanthridium derivatives as FtsZ-targeting antibacterial agents from structural simplification of natural product sanguinarine.

Journal: Bioorganic & medicinal chemistry letters

Published: January 28, 2018

Substitution of terminal amide with 1H-1,2,3-triazole: Identification of unexpected class of potent antibacterial agents.

Substitution of terminal amide with 1H-1,2,3-triazole: Identification of unexpected class of potent antibacterial agents.

Journal: Bioorganic & medicinal chemistry letters

Published: October 28, 2017

Synthesis and antibacterial activity of 5-methylphenanthridium derivatives as FtsZ inhibitors.

Synthesis and antibacterial activity of 5-methylphenanthridium derivatives as FtsZ inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: February 16, 2017

Design, synthesis and biological activity evaluation of novel 2,6-difluorobenzamide derivatives through FtsZ inhibition.

Design, synthesis and biological activity evaluation of novel 2,6-difluorobenzamide derivatives through FtsZ inhibition.

Journal: Bioorganic & medicinal chemistry letters

Published: October 05, 2016

Discovery and Optimization of NAD+-Dependent DNA Ligase Inhibitors as Novel Antibacterial Compounds.

Discovery and Optimization of NAD+-Dependent DNA Ligase Inhibitors as Novel Antibacterial Compounds.

Journal: Current pharmaceutical design

Published: May 04, 2016

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Last Updated: 09/26/2026