Fangfang Lai

State Key Laboratory Of Bioactive Substances And Functions Of Natural Medicines, Chinese Academy Of Medical Sciences & Peking Union Medical College
Beijing, 100050, China

Last Updated: 09/26/2026

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Found 49 publications

Cationic Photosensitizer-Functionalized Bacteria for Targeted Photothermal-Photodynamic Therapy with Immune Activation.

Cationic Photosensitizer-Functionalized Bacteria for Targeted Photothermal-Photodynamic Therapy with Immune Activation.

Journal: Journal of medicinal chemistry

Published: June 02, 2026

Design, Synthesis and Biological Evaluation of New Oxazolidinone Antimicrobial Agents with Low Monoamine Oxidase A Inhibition.

Design, Synthesis and Biological Evaluation of New Oxazolidinone Antimicrobial Agents with Low Monoamine Oxidase A Inhibition.

Journal: Drug design, development and therapy

Published: February 11, 2026

Novel nitric oxide-releasing triptolidenol derivatives suppress gastric cancer by targeting the folate one-carbon metabolism pathway and inducing ROS accumulation.

Novel nitric oxide-releasing triptolidenol derivatives suppress gastric cancer by targeting the folate one-carbon metabolism pathway and inducing ROS accumulation.

Journal: European journal of medicinal chemistry

Published: January 18, 2026

Melanoma cell-derived LAG-3 enhances CXCL1/8-driven MDSCs recruitment and immune escape via TRIM28-mediated IκBα degradation.

Melanoma cell-derived LAG-3 enhances CXCL1/8-driven MDSCs recruitment and immune escape via TRIM28-mediated IκBα degradation.

Journal: Journal of advanced research

Published: September 17, 2025

Total Synthesis and SARS-CoV-2 3CLpro Inhibition Activities of (±)-Tuaimenal A and Its Derivatives.

Total Synthesis and SARS-CoV-2 3CLpro Inhibition Activities of (±)-Tuaimenal A and Its Derivatives.

Journal: Journal of natural products

Published: May 19, 2025

Discovery of bromobenzyl phenyl ether derivative YPD-29B: a novel pre-clinical compound targeting the programmed cell death-1/programmed cell death-ligand 1 (PD-1/PD-L1) interaction.

Discovery of bromobenzyl phenyl ether derivative YPD-29B: a novel pre-clinical compound targeting the programmed cell death-1/programmed cell death-ligand 1 (PD-1/PD-L1) interaction.

Journal: Bioorganic & medicinal chemistry

Published: May 19, 2025

Corrigendum to "Novel Nitric oxide-releasing derivatives of pyranocarbazole as antitumor agents: Design, synthesis, biological evaluation, and nitric oxide release studies" [Eur. J. Med. Chem. 244 (2022) 114832 / EJMECH-D-22-01635R2].

Corrigendum to "Novel Nitric oxide-releasing derivatives of pyranocarbazole as antitumor agents: Design, synthesis, biological evaluation, and nitric oxide release studies" [Eur. J. Med. Chem. 244 (2022) 114832 / EJMECH-D-22-01635R2].

Journal: European journal of medicinal chemistry

Published: October 22, 2024

Design and synthesis of novel sulfur-substituted triptolide with the ability to induce autophagy through inhibition of SRSF1 expression.

Design and synthesis of novel sulfur-substituted triptolide with the ability to induce autophagy through inhibition of SRSF1 expression.

Journal: European journal of medicinal chemistry

Published: July 09, 2024

A Novel Dual Bruton's Tyrosine Kinase/Janus Kinase 3 Inhibitor Wj1113 and its Therapeutic Effects on Rheumatoid Arthritis.

A Novel Dual Bruton's Tyrosine Kinase/Janus Kinase 3 Inhibitor Wj1113 and its Therapeutic Effects on Rheumatoid Arthritis.

Journal: MedComm

Published: April 09, 2024

Rational design and optimization of novel 4-methyl quinazoline derivatives as PI3K/HDAC dual inhibitors with benzamide as zinc binding moiety for the treatment of acute myeloid leukemia.

Rational design and optimization of novel 4-methyl quinazoline derivatives as PI3K/HDAC dual inhibitors with benzamide as zinc binding moiety for the treatment of acute myeloid leukemia.

Journal: European journal of medicinal chemistry

Published: October 06, 2023

Previously undescribed tetrahydroanthraquinones from Prismatomeris tetrandra (roxb.) K. Schum with antitumor cell proliferation activities.

Previously undescribed tetrahydroanthraquinones from Prismatomeris tetrandra (roxb.) K. Schum with antitumor cell proliferation activities.

Journal: Phytochemistry

Published: September 28, 2023

Exploration and Biological Evaluation of 1,3-Diamino-7H-pyrrol[3,2-f]quinazoline Derivatives as Dihydrofolate Reductase Inhibitors.

Exploration and Biological Evaluation of 1,3-Diamino-7H-pyrrol[3,2-f]quinazoline Derivatives as Dihydrofolate Reductase Inhibitors.

Journal: Journal of medicinal chemistry

Published: September 12, 2023

Showing 1-12 of 49

Last Updated: 09/26/2026