Farah Chali

Paris, France

Last Updated: 09/26/2026

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Found 15 publications

Astrocyte-neuron combined targeting for CYP46A1 gene therapy in Huntington's disease.

Astrocyte-neuron combined targeting for CYP46A1 gene therapy in Huntington's disease.

Journal: Acta neuropathologica communications

Published: October 18, 2024

Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hallmarks of Niemann-Pick type C disease but is not sufficient to halt neurodegeneration.

Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hallmarks of Niemann-Pick type C disease but is not sufficient to halt neurodegeneration.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: July 21, 2023

Transcriptomics and Live Imaging to Define Functional Phenotypes of Microglia in Pathological Human Tissue.

Transcriptomics and Live Imaging to Define Functional Phenotypes of Microglia in Pathological Human Tissue.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: August 09, 2019

Low-Intensity Running and High-Intensity Swimming Exercises Differentially Improve Energy Metabolism in Mice With Mild Spinal Muscular Atrophy.

Low-Intensity Running and High-Intensity Swimming Exercises Differentially Improve Energy Metabolism in Mice With Mild Spinal Muscular Atrophy.

Journal: Frontiers in physiology

Published: April 06, 2019

Distinct P2Y Receptors Mediate Extension and Retraction of Microglial Processes in Epileptic and Peritumoral Human Tissue.

Distinct P2Y Receptors Mediate Extension and Retraction of Microglial Processes in Epileptic and Peritumoral Human Tissue.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: January 25, 2019

Lipid markers and related transcripts during excitotoxic neurodegeneration in kainate-treated mice.

Lipid markers and related transcripts during excitotoxic neurodegeneration in kainate-treated mice.

Journal: The European journal of neuroscience

Published: November 23, 2018

Microglial phenotypes in the human epileptic temporal lobe.

Microglial phenotypes in the human epileptic temporal lobe.

Journal: Brain : a journal of neurology

Published: March 29, 2018

Imaging pathological activities of human brain tissue in organotypic culture.

Imaging pathological activities of human brain tissue in organotypic culture.

Journal: Journal of neuroscience methods

Published: November 12, 2017

IGF-1R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice.

IGF-1R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: August 28, 2015

Long-term exercise-specific neuroprotection in spinal muscular atrophy-like mice.

Long-term exercise-specific neuroprotection in spinal muscular atrophy-like mice.

Journal: The Journal of physiology

Published: July 24, 2015

CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease.

CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease.

Journal: Brain : a journal of neurology

Published: November 04, 2014

Inhibiting cholesterol degradation induces neuronal sclerosis and epileptic activity in mouse hippocampus.

Inhibiting cholesterol degradation induces neuronal sclerosis and epileptic activity in mouse hippocampus.

Journal: The European journal of neuroscience

Published: September 29, 2014

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Last Updated: 09/26/2026