Feifei Chen

State Key Laboratory Of Bioreactor Engineering
Shanghai, 200237, China

Last Updated: 09/26/2026

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Found 25 publications

Discovery of New Teraryl γ-Lactam Derivatives as Potent Antibacterial Agents In Vitro and In Vivo through Dual Cell Wall-Membrane Inhibitions.

Discovery of New Teraryl γ-Lactam Derivatives as Potent Antibacterial Agents In Vitro and In Vivo through Dual Cell Wall-Membrane Inhibitions.

Journal: Journal of medicinal chemistry

Published: April 15, 2026

Novel Aryl Sulfonium Modification on Vancomycin to Tackle MRSA and VRE In Vitro and In Vivo through Dual Enhanced Cell-Wall and Membrane Inhibition.

Novel Aryl Sulfonium Modification on Vancomycin to Tackle MRSA and VRE In Vitro and In Vivo through Dual Enhanced Cell-Wall and Membrane Inhibition.

Journal: Journal of medicinal chemistry

Published: April 12, 2025

Design, synthesis and optimization of TarO inhibitors as multifunctional antibiotics against Methicillin-resistant Staphylococcus aureus.

Design, synthesis and optimization of TarO inhibitors as multifunctional antibiotics against Methicillin-resistant Staphylococcus aureus.

Journal: npj antimicrobials and resistance

Published: December 16, 2024

Discovery of a novel polymyxin adjuvant against multidrug-resistant gram-negative bacteria through oxidative stress modulation.

Discovery of a novel polymyxin adjuvant against multidrug-resistant gram-negative bacteria through oxidative stress modulation.

Journal: Acta pharmaceutica Sinica. B

Published: September 12, 2024

A Vancomycin-Templated DNA-Encoded Library for Combating Drug-Resistant Bacteria.

A Vancomycin-Templated DNA-Encoded Library for Combating Drug-Resistant Bacteria.

Journal: Journal of medicinal chemistry

Published: March 14, 2024

Citrate serves as a signal molecule to modulate carbon metabolism and iron homeostasis in Staphylococcus aureus.

Citrate serves as a signal molecule to modulate carbon metabolism and iron homeostasis in Staphylococcus aureus.

Journal: PLoS pathogens

Published: October 20, 2023

A facile and selective derivatization approach on kynurenine-NH2 in daptomycin, leading to the discovery of hexakynomycin to combat multidrug-resistant Gram-positive pathogens especially daptomycin-resistant bacteria.

A facile and selective derivatization approach on kynurenine-NH2 in daptomycin, leading to the discovery of hexakynomycin to combat multidrug-resistant Gram-positive pathogens especially daptomycin-resistant bacteria.

Journal: European journal of medicinal chemistry

Published: May 15, 2023

The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus.

The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus.

Journal: Virulence

Published: January 24, 2023

Modulation of MRSA virulence gene expression by the wall teichoic acid enzyme TarO.

Modulation of MRSA virulence gene expression by the wall teichoic acid enzyme TarO.

Journal: Nature communications

Published: July 01, 2022

Multifunctional biocatalysis: An unusual imine reductase.

Multifunctional biocatalysis: An unusual imine reductase.

Journal: Engineering microbiology

Published: May 01, 2022

Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus.

Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus.

Journal: Molecular microbiology

Published: December 18, 2019

Sulfonium, an Underestimated Moiety for Structural Modification, Alters the Antibacterial Profile of Vancomycin Against Multidrug-Resistant Bacteria.

Sulfonium, an Underestimated Moiety for Structural Modification, Alters the Antibacterial Profile of Vancomycin Against Multidrug-Resistant Bacteria.

Journal: Angewandte Chemie (International ed. in English)

Published: February 19, 2019

Showing 1-12 of 25

Last Updated: 09/26/2026