Fen-er H. Chen

Key Laboratory Of Natural Medicines Of The Changbai Mountain
Longjing, 133002, China

Last Updated: 09/26/2026

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Found 166 publications

Molybdenum-Catalyzed Intramolecular Deoxygenative Annulation of 2-(Formamido)aryl Ketones to Access 3-Monosubstituted Oxindoles.

Molybdenum-Catalyzed Intramolecular Deoxygenative Annulation of 2-(Formamido)aryl Ketones to Access 3-Monosubstituted Oxindoles.

Journal: Organic letters

Published: July 07, 2026

A Mechanism-Guided Strategy by Weighting Key Reaction States for Rational Engineering of ω-Transaminase toward Bulky Chiral Amines.

A Mechanism-Guided Strategy by Weighting Key Reaction States for Rational Engineering of ω-Transaminase toward Bulky Chiral Amines.

Journal: Organic letters

Published: June 15, 2026

Total synthesis of γ-tocopherol via asymmetric 1,4-conjugate addition of alkyl Grignard reagents to 2-methyl chromone.

Total synthesis of γ-tocopherol via asymmetric 1,4-conjugate addition of alkyl Grignard reagents to 2-methyl chromone.

Journal: Organic & biomolecular chemistry

Published: May 18, 2026

Correction to "Rational Design of Broad-Spectrum Non-Nucleoside Reverse Transcriptase Inhibitors via Pharmacophore-Oriented Generative Artificial Intelligence".

Correction to "Rational Design of Broad-Spectrum Non-Nucleoside Reverse Transcriptase Inhibitors via Pharmacophore-Oriented Generative Artificial Intelligence".

Journal: Journal of medicinal chemistry

Published: April 20, 2026

Highly Regio- and Enantioselective Catalytic 1,6-Conjugate Addition of Grignard Reagents to Cyclic Dienones.

Highly Regio- and Enantioselective Catalytic 1,6-Conjugate Addition of Grignard Reagents to Cyclic Dienones.

Journal: Organic letters

Published: April 09, 2026

Rational Design of Broad-Spectrum Non-Nucleoside Reverse Transcriptase Inhibitors via Pharmacophore-Oriented Generative Artificial Intelligence.

Rational Design of Broad-Spectrum Non-Nucleoside Reverse Transcriptase Inhibitors via Pharmacophore-Oriented Generative Artificial Intelligence.

Journal: Journal of medicinal chemistry

Published: March 30, 2026

Visible-Light Induced Dehydrogenative Cross-Coupling of Enamides with Hydrocarbons Enabled by Aryl Thianthrenium Salt.

Visible-Light Induced Dehydrogenative Cross-Coupling of Enamides with Hydrocarbons Enabled by Aryl Thianthrenium Salt.

Journal: Organic letters

Published: March 26, 2026

Harnessing Unique Boron Chemistry to Develop a New Class of Non-hydroxamate HDAC Inhibitors with Validated In Vivo Efficacy.

Harnessing Unique Boron Chemistry to Develop a New Class of Non-hydroxamate HDAC Inhibitors with Validated In Vivo Efficacy.

Journal: Journal of medicinal chemistry

Published: February 24, 2026

Discovery of novel coumarin-containing triazolo[1,5-a]pyrimidine derivatives as potent ABCB1 inhibitor for modulation of multidrug resistance.

Discovery of novel coumarin-containing triazolo[1,5-a]pyrimidine derivatives as potent ABCB1 inhibitor for modulation of multidrug resistance.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: February 19, 2026

Cyclization-Inspired Structural Optimization: Designing Potent Non-nucleoside Reverse Transcriptase Inhibitors with Enhanced Safety and Selectivity.

Cyclization-Inspired Structural Optimization: Designing Potent Non-nucleoside Reverse Transcriptase Inhibitors with Enhanced Safety and Selectivity.

Journal: Journal of medicinal chemistry

Published: January 09, 2026

Enantioselective Synthesis of Functionalized 2,2-Disubstituted Piperidines Enabled by Pd-Catalyzed Decarboxylative Asymmetric Allylic Alkylation.

Enantioselective Synthesis of Functionalized 2,2-Disubstituted Piperidines Enabled by Pd-Catalyzed Decarboxylative Asymmetric Allylic Alkylation.

Journal: Organic letters

Published: December 31, 2025

Cu-Catalyzed dynamic kinetic asymmetric allylation enabled enantioselective assembly of sterically congested triaryl tertiary alcohols.

Cu-Catalyzed dynamic kinetic asymmetric allylation enabled enantioselective assembly of sterically congested triaryl tertiary alcohols.

Journal: Nature communications

Published: December 24, 2025

Showing 1-12 of 166

Last Updated: 09/26/2026