Fengchan Han

Key Laboratory For Genetic Hearing Disorders In Shandong, 346 Guanhai Road
Yantai, 264003, China

Last Updated: 09/26/2026

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Found 25 publications

Inhibition of the ILK-AKT pathway by upregulation of PARVB contributes to the cochlear cell death in Fascin2 gene knockout mice.

Inhibition of the ILK-AKT pathway by upregulation of PARVB contributes to the cochlear cell death in Fascin2 gene knockout mice.

Journal: Cell death discovery
Published: November 21, 2023

Loss of Fascin2 increases susceptibility to cisplatin-induced hearing impairment and cochlear cell apoptosis in mice.

Loss of Fascin2 increases susceptibility to cisplatin-induced hearing impairment and cochlear cell apoptosis in mice.

Journal: Journal of otology
Published: August 26, 2023

Effect of downregulated citrate synthase on oxidative phosphorylation signaling pathway in HEI-OC1 cells.

Effect of downregulated citrate synthase on oxidative phosphorylation signaling pathway in HEI-OC1 cells.

Journal: Proteome science
Published: June 26, 2022

H55 N variation in citrate synthase leads to decrement in the enzyme activity and transport rate to mitochondria in HEI-OC1 cells.

H55 N variation in citrate synthase leads to decrement in the enzyme activity and transport rate to mitochondria in HEI-OC1 cells.

Journal: Biochemical and biophysical research communications
Published: April 09, 2022

A newly identified mutation (c.2029 C > T) in SLC26A4 gene is associated with enlarged vestibular aqueducts in a Chinese family.

A newly identified mutation (c.2029 C > T) in SLC26A4 gene is associated with enlarged vestibular aqueducts in a Chinese family.

Journal: BMC medical genomics
Published: June 19, 2021

Role of TGF-β1-mediated epithelial-mesenchymal transition in the pathogenesis of tympanosclerosis.

Role of TGF-β1-mediated epithelial-mesenchymal transition in the pathogenesis of tympanosclerosis.

Journal: Experimental and therapeutic medicine
Published: May 14, 2020

Otoprotective Effects of α-lipoic Acid on A/J Mice With Age-related Hearing Loss.

Otoprotective Effects of α-lipoic Acid on A/J Mice With Age-related Hearing Loss.

Journal: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Published: April 14, 2020

ALA protects against ERS-mediated apoptosis in a cochlear cell model with low citrate synthase expression.

ALA protects against ERS-mediated apoptosis in a cochlear cell model with low citrate synthase expression.

Journal: Archives of biochemistry and biophysics
Published: January 28, 2020

A novel mutation in TRIOBP gene leading to congenital deafness in a Chinese family.

A novel mutation in TRIOBP gene leading to congenital deafness in a Chinese family.

Journal: BMC medical genetics
Published: November 13, 2019

Characterization of the early pathology of cochlear stereocilia in four inbred mouse strains with progressive hearing loss.

Characterization of the early pathology of cochlear stereocilia in four inbred mouse strains with progressive hearing loss.

Journal: Histology and histopathology
Published: January 25, 2019

Null Mutation of the Fascin2 Gene by TALEN Leading to Progressive Hearing Loss and Retinal Degeneration in C57BL/6J Mice.

Null Mutation of the Fascin2 Gene by TALEN Leading to Progressive Hearing Loss and Retinal Degeneration in C57BL/6J Mice.

Journal: G3 (Bethesda, Md.)
Published: August 08, 2018

Recombinant protein of the first two ectodomains of cadherin 23 from erl mice shows impairment in Ca2+-dependent proteolysis protection.

Recombinant protein of the first two ectodomains of cadherin 23 from erl mice shows impairment in Ca2+-dependent proteolysis protection.

Journal: Protein expression and purification
Published: May 12, 2017
Showing 1-12 of 25

Last Updated: 09/26/2026