Fenju Wei

Key Laboratory Of Chemical Biology, Ji'nan
250012, China

Last Updated: 09/26/2026

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Found 11 publications

Current medicinal chemistry strategies in the discovery of novel HIV-1 ribonuclease H inhibitors.

Current medicinal chemistry strategies in the discovery of novel HIV-1 ribonuclease H inhibitors.

Journal: European journal of medicinal chemistry

Published: August 11, 2022

Design, synthesis, and biological evaluation of novel double-winged galloyl derivatives as HIV-1 RNase H inhibitors.

Design, synthesis, and biological evaluation of novel double-winged galloyl derivatives as HIV-1 RNase H inhibitors.

Journal: European journal of medicinal chemistry

Published: May 19, 2022

Discovery, optimization, and target identification of novel coumarin derivatives as HIV-1 reverse transcriptase-associated ribonuclease H inhibitors.

Discovery, optimization, and target identification of novel coumarin derivatives as HIV-1 reverse transcriptase-associated ribonuclease H inhibitors.

Journal: European journal of medicinal chemistry

Published: May 03, 2021

Discovery and optimizing polycyclic pyridone compounds as anti-HBV agents.

Discovery and optimizing polycyclic pyridone compounds as anti-HBV agents.

Journal: Expert opinion on therapeutic patents

Published: August 05, 2020

Structure-Activity Relationship Exploration of NNIBP Tolerant Region I Leads to Potent HIV-1 NNRTIs.

Structure-Activity Relationship Exploration of NNIBP Tolerant Region I Leads to Potent HIV-1 NNRTIs.

Journal: ACS infectious diseases

Published: July 04, 2020

Structure-Based Bioisosterism Yields HIV-1 NNRTIs with Improved Drug-Resistance Profiles and Favorable Pharmacokinetic Properties.

Structure-Based Bioisosterism Yields HIV-1 NNRTIs with Improved Drug-Resistance Profiles and Favorable Pharmacokinetic Properties.

Journal: Journal of medicinal chemistry

Published: April 16, 2020

In situ click chemistry-based rapid discovery of novel HIV-1 NNRTIs by exploiting the hydrophobic channel and tolerant regions of NNIBP.

In situ click chemistry-based rapid discovery of novel HIV-1 NNRTIs by exploiting the hydrophobic channel and tolerant regions of NNIBP.

Journal: European journal of medicinal chemistry

Published: February 16, 2020

Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel.

Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel.

Journal: Journal of medicinal chemistry

Published: January 15, 2020

Exploring the hydrophobic channel of NNIBP leads to the discovery of novel piperidine-substituted thiophene[3,2-d]pyrimidine derivatives as potent HIV-1 NNRTIs.

Exploring the hydrophobic channel of NNIBP leads to the discovery of novel piperidine-substituted thiophene[3,2-d]pyrimidine derivatives as potent HIV-1 NNRTIs.

Journal: Acta pharmaceutica Sinica. B

Published: May 14, 2019

Identification of Dihydrofuro[3,4- d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties.

Identification of Dihydrofuro[3,4- d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties.

Journal: Journal of medicinal chemistry

Published: January 10, 2019

Development of a practical synthesis of etravirine via a microwave-promoted amination.

Development of a practical synthesis of etravirine via a microwave-promoted amination.

Journal: Chemistry Central journal

Published: October 06, 2018

Showing 1-11 of 11

Last Updated: 09/26/2026