Filip Cuyckens
Janssen R&D
Beerse, VLG, Belgium
Beerse, VLG, Belgium
Last Updated: 09/26/2026
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Found 58 publications
Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends.
Journal: Clinical pharmacology and therapeutics
Published: December 12, 2025
Inductively coupled plasma mass spectrometry as a sensitive non-radioactive alternative for quantitative analysis in drug metabolism studies based on fluorine detection.
Journal: Analytical and bioanalytical chemistry
Published: December 01, 2025
Advanced quench correction model for quantitative offline radioactivity counting in in vivo drug metabolism studies.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: August 19, 2025
Guided Sample Pooling in Human Mass Balance Studies: A Recommended Strategic Decision Framework.
Journal: Clinical pharmacology and therapeutics
Published: June 26, 2025
Bioactivation of the β-Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor Atabecestat Leads to Protein Adduct Formation on Glutathione S-Transferase Pi.
Journal: Chemical research in toxicology
Published: May 06, 2025
Absorption, distribution, metabolism, and excretion of an antiviral drug-Fc conjugate CD388 following subcutaneous administration of 14C-CD388 in the rat.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: February 20, 2025
Investigation into Drug-Induced Liver Damage Using Multimodal Mass Spectrometry Imaging.
Journal: Journal of the American Society for Mass Spectrometry
Published: January 17, 2025
CYP3A4-Mediated Bioactivation of the β-Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor JNJ-54861911 Results in Redox-Neutral Addition of Glutathione via Catalysis by Glutathione S-Transferase α1, Identified as the Major Target Protein in Human Hepatocytes.
Journal: Chemical research in toxicology
Published: December 11, 2024
Metabolite Bioanalysis in Drug Development: Recommendations from the IQ Consortium Metabolite Bioanalysis Working Group.
Journal: Clinical pharmacology and therapeutics
Published: September 19, 2023
Recommendations on the Use of Multiple Labels in Human Mass Balance Studies.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: September 18, 2023
Non-Labeled, Stable Labeled, or Radiolabelled Approaches for Provision of Intravenous Pharmacokinetics in Humans: A Discussion Piece.
Journal: Clinical pharmacology and therapeutics
Published: August 21, 2023
Considerations for Human ADME Strategy and Design Paradigm Shift(s) - An Industry White Paper.
Journal: Clinical pharmacology and therapeutics
Published: February 18, 2022
Last Updated: 09/26/2026