Filip Van Petegem

2350 Health Sciences Mall
Vancouver, BC, Canada

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 123 publications

A neurocutaneous NaV1.8 channelopathy underlies a genetic subtype of primary idiopathic hyperhidrosis.

A neurocutaneous NaV1.8 channelopathy underlies a genetic subtype of primary idiopathic hyperhidrosis.

Journal: Science advances

Published: July 17, 2026

Distinct effects of disease-associated mutations in the proximal C-linker on negatively cooperative binding of cyclic nucleotides to the human HCN4 channel.

Distinct effects of disease-associated mutations in the proximal C-linker on negatively cooperative binding of cyclic nucleotides to the human HCN4 channel.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire

Published: June 04, 2026

Distinct effects of disease-associated mutations in the proximal C-linker on negatively cooperative binding of cyclic nucleotides to the human HCN4 channel.

Distinct effects of disease-associated mutations in the proximal C-linker on negatively cooperative binding of cyclic nucleotides to the human HCN4 channel.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire

Published: June 04, 2026

Differential regulation of β1-dependent voltage shifts and kinetic modulation by an extracellular glutamate in NaV1.6 VSDIV.

Differential regulation of β1-dependent voltage shifts and kinetic modulation by an extracellular glutamate in NaV1.6 VSDIV.

Journal: The Journal of general physiology

Published: March 30, 2026

Structural enzymology of a Fusarium graminearum aldehyde oxidase reveals a distinct active-site and reactivity versus its paralog galactose oxidase.

Structural enzymology of a Fusarium graminearum aldehyde oxidase reveals a distinct active-site and reactivity versus its paralog galactose oxidase.

Journal: The Biochemical journal

Published: January 12, 2026

Direct Therapeutic Modulation of RYR2 Activity by CMYA5.

Direct Therapeutic Modulation of RYR2 Activity by CMYA5.

Journal: Circulation

Published: October 20, 2025

Phosphorylation of RYR1 at Ser2902 decreases Ca2+ leak in skeletal muscle and susceptibility to malignant hyperthermia and heat stroke.

Phosphorylation of RYR1 at Ser2902 decreases Ca2+ leak in skeletal muscle and susceptibility to malignant hyperthermia and heat stroke.

Journal: Science signaling

Published: October 07, 2025

An inter-subunit path is required for entropically-driven and negatively cooperative binding of cyclic nucleotides in the HCN2 channel.

An inter-subunit path is required for entropically-driven and negatively cooperative binding of cyclic nucleotides in the HCN2 channel.

Journal: Communications biology

Published: August 08, 2025

Identification of novel potentially causative RYR1 variants in individuals with malignant hyperthermia susceptibility.

Identification of novel potentially causative RYR1 variants in individuals with malignant hyperthermia susceptibility.

Journal: Neuromuscular disorders : NMD

Published: June 24, 2025

A robust expression system reveals distinct gating mechanisms and calmodulin regulation of NaV1.9 channels.

A robust expression system reveals distinct gating mechanisms and calmodulin regulation of NaV1.9 channels.

Journal: Science advances

Published: May 28, 2025

Cryo-electron microscopy reveals sequential binding and activation of Ryanodine Receptors by statin triplets.

Cryo-electron microscopy reveals sequential binding and activation of Ryanodine Receptors by statin triplets.

Journal: Nature communications

Published: May 22, 2025

Structural insights into insect-selective sodium channel toxins drive AI-enhanced biopesticide design.

Structural insights into insect-selective sodium channel toxins drive AI-enhanced biopesticide design.

Journal: Nature communications

Published: April 02, 2025

Showing 1-12 of 123

Last Updated: 09/26/2026