Finbarr P. O'harte

Coleraine, NIR, United Kingdom

Last Updated: 09/26/2026

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Found 35 publications

Unimolecular GLP-1/Apelin Hybrid Peptides Cause Prominent Appetite Suppression, as Well as Enhancing Insulin Secretion, Beta-Cell Survival and Glycaemic Regulation.

Unimolecular GLP-1/Apelin Hybrid Peptides Cause Prominent Appetite Suppression, as Well as Enhancing Insulin Secretion, Beta-Cell Survival and Glycaemic Regulation.

Journal: Diabetes, obesity & metabolism

Published: January 23, 2026

Impact of novel amino acid substituted and acylated spexin analogues on pancreatic beta-cell function, appetite and glucose homeostasis.

Impact of novel amino acid substituted and acylated spexin analogues on pancreatic beta-cell function, appetite and glucose homeostasis.

Journal: Molecular and cellular endocrinology

Published: June 04, 2025

An update on galanin and spexin and their potential for the treatment of type 2 diabetes and related metabolic disorders.

An update on galanin and spexin and their potential for the treatment of type 2 diabetes and related metabolic disorders.

Journal: Peptides

Published: August 11, 2023

The glucagon receptor antagonist desHis1Pro4Glu9-glucagon(Lys12PAL) alters alpha-cell turnover and lineage in mice, but does not cause alpha-cell hyperplasia.

The glucagon receptor antagonist desHis1Pro4Glu9-glucagon(Lys12PAL) alters alpha-cell turnover and lineage in mice, but does not cause alpha-cell hyperplasia.

Journal: Molecular and cellular endocrinology

Published: February 02, 2023

Sustained glucagon receptor antagonism in insulin-deficient high-fat-fed mice.

Sustained glucagon receptor antagonism in insulin-deficient high-fat-fed mice.

Journal: The Journal of endocrinology

Published: August 19, 2022

Metabolic effects of combined glucagon receptor antagonism and glucagon-like peptide-1 receptor agonism in high fat fed mice.

Metabolic effects of combined glucagon receptor antagonism and glucagon-like peptide-1 receptor agonism in high fat fed mice.

Journal: Biochimie

Published: January 27, 2022

Dual-agonist incretin peptides from fish with potential for obesity-related Type 2 diabetes therapy - A review.

Dual-agonist incretin peptides from fish with potential for obesity-related Type 2 diabetes therapy - A review.

Journal: Peptides

Published: October 20, 2021

Potential Therapeutic Role for Apelin and Related Peptides in Diabetes: An Update.

Potential Therapeutic Role for Apelin and Related Peptides in Diabetes: An Update.

Journal: Clinical medicine insights. Endocrinology and diabetes

Published: August 11, 2021

Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis.

Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis.

Journal: Autophagy

Published: August 02, 2021

Physicochemical, Nutritional and In Vitro Antidiabetic Characterisation of Blue Whiting (Micromesistiuspoutassou) Protein Hydrolysates.

Physicochemical, Nutritional and In Vitro Antidiabetic Characterisation of Blue Whiting (Micromesistiuspoutassou) Protein Hydrolysates.

Journal: Marine drugs

Published: May 31, 2021

Proglucagon-Derived Peptides as Therapeutics.

Proglucagon-Derived Peptides as Therapeutics.

Journal: Frontiers in endocrinology

Published: April 01, 2021

Macroalgal protein hydrolysates from Palmaria palmata influence the 'incretin effect' in vitro via DPP-4 inhibition and upregulation of insulin, GLP-1 and GIP secretion.

Macroalgal protein hydrolysates from Palmaria palmata influence the 'incretin effect' in vitro via DPP-4 inhibition and upregulation of insulin, GLP-1 and GIP secretion.

Journal: European journal of nutrition

Published: November 16, 2020

Showing 1-12 of 35

Last Updated: 09/26/2026