Fiona Grueninger-Leitch

Basel, BS, Switzerland

Last Updated: 09/26/2026

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Found 18 publications

Correction: Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer's disease.

Correction: Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer's disease.

Journal: Acta neuropathologica communications

Published: February 14, 2024

Discovery of Orally Available and Brain Penetrant AEP Inhibitors.

Discovery of Orally Available and Brain Penetrant AEP Inhibitors.

Journal: Journal of medicinal chemistry

Published: December 13, 2023

Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation.

Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation.

Journal: Neuron

Published: August 16, 2022

Identification and characterization of a MAPT-targeting locked nucleic acid antisense oligonucleotide therapeutic for tauopathies.

Identification and characterization of a MAPT-targeting locked nucleic acid antisense oligonucleotide therapeutic for tauopathies.

Journal: Molecular therapy. Nucleic acids

Published: October 20, 2021

Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.

Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.

Journal: Cell

Published: January 27, 2020

Chemically-defined camelid antibody bioconjugate for the magnetic resonance imaging of Alzheimer's disease.

Chemically-defined camelid antibody bioconjugate for the magnetic resonance imaging of Alzheimer's disease.

Journal: mAbs

Published: June 29, 2017

Sembragiline: A Novel, Selective Monoamine Oxidase Type B Inhibitor for the Treatment of Alzheimer's Disease.

Sembragiline: A Novel, Selective Monoamine Oxidase Type B Inhibitor for the Treatment of Alzheimer's Disease.

Journal: The Journal of pharmacology and experimental therapeutics

Published: March 24, 2017

Region-specific permeability of the blood-brain barrier upon pericyte loss.

Region-specific permeability of the blood-brain barrier upon pericyte loss.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Published: March 10, 2017

Camelid single-domain antibodies: A versatile tool for in vivo imaging of extracellular and intracellular brain targets.

Camelid single-domain antibodies: A versatile tool for in vivo imaging of extracellular and intracellular brain targets.

Journal: Journal of controlled release : official journal of the Controlled Release Society

Published: June 23, 2016

Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy.

Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy.

Journal: Acta neuropathologica communications

Published: February 17, 2016

Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier.

Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier.

Journal: Scientific reports

Published: October 09, 2015

Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease.

Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease.

Journal: Brain : a journal of neurology

Published: August 03, 2014

Showing 1-12 of 18

Last Updated: 09/26/2026