Flavia B. Lopes

Diadema, SP, Brazil

Last Updated: 09/26/2026

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Found 11 publications

Probing Cinnamamides and Benzamides as Anthelmintics: Discovery of Potent Drug-Like Agents Against Angiostrongylus cantonensis.

Probing Cinnamamides and Benzamides as Anthelmintics: Discovery of Potent Drug-Like Agents Against Angiostrongylus cantonensis.

Journal: Chemical biology & drug design

Published: March 06, 2026

Preclinical characterization of the efficacy and safety of histamine H3 receptor antagonist, LINS01022, as a novel analgesic for chronic neuropathic pain treatment.

Preclinical characterization of the efficacy and safety of histamine H3 receptor antagonist, LINS01022, as a novel analgesic for chronic neuropathic pain treatment.

Journal: European journal of pharmacology

Published: February 17, 2026

Multitargeted Aza-Arylcarboxamides for Neurodegenerative Diseases: Potent Histamine H3 Receptor Ligands with Anticholinesterase and Metal-Chelating Activities.

Multitargeted Aza-Arylcarboxamides for Neurodegenerative Diseases: Potent Histamine H3 Receptor Ligands with Anticholinesterase and Metal-Chelating Activities.

Journal: ACS chemical neuroscience

Published: January 29, 2026

Structural Exploitation of Cinnarizine Identified Novel Drug-Like Anthelmintic Agents Against Angiostrongylus cantonensis.

Structural Exploitation of Cinnarizine Identified Novel Drug-Like Anthelmintic Agents Against Angiostrongylus cantonensis.

Journal: ACS infectious diseases

Published: October 01, 2025

Dimethyltryptamine and harmine, components of ayahuasca, prevented cocaine-induced apoptosis in SH-SY5Y human neuroblastoma cells.

Dimethyltryptamine and harmine, components of ayahuasca, prevented cocaine-induced apoptosis in SH-SY5Y human neuroblastoma cells.

Journal: Archives of toxicology

Published: August 07, 2025

Discovery of clocinizine as a potential oral drug against Schistosoma mansoni infection.

Discovery of clocinizine as a potential oral drug against Schistosoma mansoni infection.

Journal: Scientific reports

Published: December 17, 2024

Homologous acetylenic acetogenins from Porcelia macrocarpa R.E. (Fries) displayed potent activity against amastigotes from Trypanosoma cruzi.

Homologous acetylenic acetogenins from Porcelia macrocarpa R.E. (Fries) displayed potent activity against amastigotes from Trypanosoma cruzi.

Journal: Phytochemistry

Published: June 13, 2024

Tackling Neuroinflammation in Cognitive Disorders with Single-targeted and Multi-targeted Histamine H3 Receptor Modulators.

Tackling Neuroinflammation in Cognitive Disorders with Single-targeted and Multi-targeted Histamine H3 Receptor Modulators.

Journal: Current topics in medicinal chemistry

Published: April 09, 2024

Multitargeting approaches to cognitive impairment: Synthesis of aryl-alkylpiperazines and assessment at cholinesterases, histamine H3 and dopamine D3 receptors.

Multitargeting approaches to cognitive impairment: Synthesis of aryl-alkylpiperazines and assessment at cholinesterases, histamine H3 and dopamine D3 receptors.

Journal: Bioorganic & medicinal chemistry

Published: October 07, 2022

Evaluation of the histamine H3 receptor antagonists from LINS01 series as cholinesterases inhibitors: Enzymatic and modeling studies.

Evaluation of the histamine H3 receptor antagonists from LINS01 series as cholinesterases inhibitors: Enzymatic and modeling studies.

Journal: Chemical biology & drug design

Published: May 20, 2022

Histamine H3 receptor and cholinesterases as synergistic targets for cognitive decline: Strategies to the rational design of multitarget ligands.

Histamine H3 receptor and cholinesterases as synergistic targets for cognitive decline: Strategies to the rational design of multitarget ligands.

Journal: Chemical biology & drug design

Published: April 05, 2021

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Last Updated: 09/26/2026