Flavio S. Emery

Ribeirao Preto, SP 14040903, Brazil

Last Updated: 09/26/2026

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Found 24 publications

5‑Nitrofuran-Semicarbazone Hybrids as Antitrypanosomal Agents: Structure-Activity Relationship and Nitroreductase Activation.

5‑Nitrofuran-Semicarbazone Hybrids as Antitrypanosomal Agents: Structure-Activity Relationship and Nitroreductase Activation.

Journal: ACS medicinal chemistry letters

Published: April 13, 2026

Quinazolinones as Bioisosteres of Naphthoquinones: A Path to Potent HsDHODH Inhibitors with Optimized Properties.

Quinazolinones as Bioisosteres of Naphthoquinones: A Path to Potent HsDHODH Inhibitors with Optimized Properties.

Journal: ACS medicinal chemistry letters

Published: April 28, 2025

Targeting dihydroorotate dehydrogenase (DHODH) for host-directed therapy: Discovery of a novel alkyne-based scaffold inhibitor effective against SARS-CoV-2.

Targeting dihydroorotate dehydrogenase (DHODH) for host-directed therapy: Discovery of a novel alkyne-based scaffold inhibitor effective against SARS-CoV-2.

Journal: European journal of medicinal chemistry

Published: January 26, 2025

Development of Novel Isoindolone-Based Compounds against Trypanosoma brucei rhodesiense.

Development of Novel Isoindolone-Based Compounds against Trypanosoma brucei rhodesiense.

Journal: ChemistryOpen

Published: July 21, 2021

Synthesis and Structure-Activity Relationships of Imidazopyridine/Pyrimidine- and Furopyridine-Based Anti-infective Agents against Trypanosomiases.

Synthesis and Structure-Activity Relationships of Imidazopyridine/Pyrimidine- and Furopyridine-Based Anti-infective Agents against Trypanosomiases.

Journal: ChemMedChem

Published: August 13, 2020

Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni.

Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni.

Journal: The FEBS journal

Published: April 08, 2020

Targeted uptake of folic acid-functionalized polymeric nanoparticles loading glycoalkaloidic extract in vitro and in vivo assays.

Targeted uptake of folic acid-functionalized polymeric nanoparticles loading glycoalkaloidic extract in vitro and in vivo assays.

Journal: Colloids and surfaces. B, Biointerfaces

Published: February 09, 2020

Structure-activity relationships and mechanism of action of tetragomycin derivatives as inhibitors of Staphylococcus aureus staphyloxanthin biosynthesis.

Structure-activity relationships and mechanism of action of tetragomycin derivatives as inhibitors of Staphylococcus aureus staphyloxanthin biosynthesis.

Journal: Microbial pathogenesis

Published: December 12, 2019

Ligand-based design, synthesis and biochemical evaluation of potent and selective inhibitors of Schistosoma mansoni dihydroorotate dehydrogenase.

Ligand-based design, synthesis and biochemical evaluation of potent and selective inhibitors of Schistosoma mansoni dihydroorotate dehydrogenase.

Journal: European journal of medicinal chemistry

Published: November 19, 2018

β-amino alcohols and their respective 2-phenyl-N-alkyl aziridines as potential DNA minor groove binders.

β-amino alcohols and their respective 2-phenyl-N-alkyl aziridines as potential DNA minor groove binders.

Journal: European journal of medicinal chemistry

Published: May 28, 2018

On the synthesis of quinone-based BODIPY hybrids: New insights on antitumor activity and mechanism of action in cancer cells.

On the synthesis of quinone-based BODIPY hybrids: New insights on antitumor activity and mechanism of action in cancer cells.

Journal: Bioorganic & medicinal chemistry letters

Published: August 02, 2017

The 3-phenylcoumarin derivative 6,7-dihydroxy-3-[3',4'-methylenedioxyphenyl]-coumarin downmodulates the FcγR- and CR-mediated oxidative metabolism and elastase release in human neutrophils: Possible mechanisms underlying inhibition of the formation and release of neutrophil extracellular traps.

The 3-phenylcoumarin derivative 6,7-dihydroxy-3-[3',4'-methylenedioxyphenyl]-coumarin downmodulates the FcγR- and CR-mediated oxidative metabolism and elastase release in human neutrophils: Possible mechanisms underlying inhibition of the formation and release of neutrophil extracellular traps.

Journal: Free radical biology & medicine

Published: July 22, 2017

Showing 1-12 of 24

Last Updated: 09/26/2026