Florence Leroux

Lille, 59000, France

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 49 publications

Enhancing antibiotic activity against Escherichia coli and Klebsiella pneumoniae with optimised pyridylpiperazine AcrAB-TolC efflux pump inhibitors.

Enhancing antibiotic activity against Escherichia coli and Klebsiella pneumoniae with optimised pyridylpiperazine AcrAB-TolC efflux pump inhibitors.

Journal: European journal of medicinal chemistry

Published: May 01, 2026

Exploiting DprE2 pathway redundancy to enhance potency and overcome resistance to pretomanid in Mycobacterium tuberculosis.

Exploiting DprE2 pathway redundancy to enhance potency and overcome resistance to pretomanid in Mycobacterium tuberculosis.

Journal: npj antimicrobials and resistance

Published: February 03, 2026

Optimizing the Antibiotic Potency and Metabolic Stability of Pyridomycin Using a Semisynthetic Approach.

Optimizing the Antibiotic Potency and Metabolic Stability of Pyridomycin Using a Semisynthetic Approach.

Journal: Journal of medicinal chemistry

Published: January 27, 2026

A new chemotype that opens the S2∗ pocket of the 3CL protease exhibits antiviral activity against SARS-CoV-2.

A new chemotype that opens the S2∗ pocket of the 3CL protease exhibits antiviral activity against SARS-CoV-2.

Journal: European journal of medicinal chemistry

Published: October 01, 2025

Discovery of pyrimidine-based small activators of insulin degrading enzyme.

Discovery of pyrimidine-based small activators of insulin degrading enzyme.

Journal: European journal of medicinal chemistry

Published: June 10, 2025

Discovery of New Nanomolar Selective IRAP Inhibitors.

Discovery of New Nanomolar Selective IRAP Inhibitors.

Journal: Journal of medicinal chemistry

Published: February 07, 2025

Enhancing antitumour response to proteasome inhibitors with inhibitors of insulin-degrading enzyme, a new molecular vulnerability in multiple myeloma.

Enhancing antitumour response to proteasome inhibitors with inhibitors of insulin-degrading enzyme, a new molecular vulnerability in multiple myeloma.

Journal: British journal of pharmacology

Published: October 14, 2024

First fragment-based screening identifies new chemotypes inhibiting ERAP1-metalloprotease.

First fragment-based screening identifies new chemotypes inhibiting ERAP1-metalloprotease.

Journal: European journal of medicinal chemistry

Published: July 26, 2024

N-acylbenzimidazoles as selective Acylators of the catalytic cystein of the coronavirus 3CL protease.

N-acylbenzimidazoles as selective Acylators of the catalytic cystein of the coronavirus 3CL protease.

Journal: European journal of medicinal chemistry

Published: June 13, 2024

Identification of new correctors for traffic-defective ABCB4 variants by a high-content screening approach.

Identification of new correctors for traffic-defective ABCB4 variants by a high-content screening approach.

Journal: Communications biology

Published: February 06, 2024

Regioselective and Stereoselective Synthesis of Parthenolide Analogs by Acyl Nitroso-Ene Reaction and Their Biological Evaluation against Mycobacterium tuberculosis.

Regioselective and Stereoselective Synthesis of Parthenolide Analogs by Acyl Nitroso-Ene Reaction and Their Biological Evaluation against Mycobacterium tuberculosis.

Journal: International journal of molecular sciences

Published: November 03, 2023

Discovery, Structure-Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5.

Discovery, Structure-Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5.

Journal: Journal of medicinal chemistry

Published: August 28, 2023

Showing 1-12 of 49

Last Updated: 09/26/2026