Florian Bolze

Freising, BY 85354, Germany

Last Updated: 09/26/2026

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Found 13 publications

Long-Acting Human PASylated Leptin Reaches the Murine Central Nervous System and Offers Potential for Optimized Replacement Therapy.

Long-Acting Human PASylated Leptin Reaches the Murine Central Nervous System and Offers Potential for Optimized Replacement Therapy.

Journal: Molecular pharmaceutics
Published: May 07, 2025

Kisspeptin-52 partially rescues the activity of the hypothalamus-pituitary-gonadal axis in underweight male rats dosed with an anti-obesity compound.

Kisspeptin-52 partially rescues the activity of the hypothalamus-pituitary-gonadal axis in underweight male rats dosed with an anti-obesity compound.

Journal: Toxicology and applied pharmacology
Published: May 20, 2020

The Effect of Diet-induced Obesity on Toxicological Parameters in the Polygenic Sprague-Dawley Rat Model.

The Effect of Diet-induced Obesity on Toxicological Parameters in the Polygenic Sprague-Dawley Rat Model.

Journal: Toxicologic pathology
Published: October 23, 2018

High-Fat Diet Accelerates Carcinogenesis in a Mouse Model of Barrett's Esophagus via Interleukin 8 and Alterations to the Gut Microbiome.

High-Fat Diet Accelerates Carcinogenesis in a Mouse Model of Barrett's Esophagus via Interleukin 8 and Alterations to the Gut Microbiome.

Journal: Gastroenterology
Published: August 29, 2018

Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation.

Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation.

Journal: Cell
Published: March 14, 2018

Aminoglycosides, but not PTC124 (Ataluren), rescue nonsense mutations in the leptin receptor and in luciferase reporter genes.

Aminoglycosides, but not PTC124 (Ataluren), rescue nonsense mutations in the leptin receptor and in luciferase reporter genes.

Journal: Scientific reports
Published: January 13, 2017

Treatment of diet-induced lipodystrophic C57BL/6J mice with long-acting PASylated leptin normalises insulin sensitivity and hepatic steatosis by promoting lipid utilisation.

Treatment of diet-induced lipodystrophic C57BL/6J mice with long-acting PASylated leptin normalises insulin sensitivity and hepatic steatosis by promoting lipid utilisation.

Journal: Diabetologia
Published: March 10, 2016

Long-Acting PASylated Leptin Ameliorates Obesity by Promoting Satiety and Preventing Hypometabolism in Leptin-Deficient Lep(ob/ob) Mice.

Long-Acting PASylated Leptin Ameliorates Obesity by Promoting Satiety and Preventing Hypometabolism in Leptin-Deficient Lep(ob/ob) Mice.

Journal: Endocrinology
Published: October 23, 2015

PASylation of Murine Leptin Leads to Extended Plasma Half-Life and Enhanced in Vivo Efficacy.

PASylation of Murine Leptin Leads to Extended Plasma Half-Life and Enhanced in Vivo Efficacy.

Journal: Molecular pharmaceutics
Published: March 27, 2015

Intrinsic differences in BRITE adipogenesis of primary adipocytes from two different mouse strains.

Intrinsic differences in BRITE adipogenesis of primary adipocytes from two different mouse strains.

Journal: Biochimica et biophysica acta
Published: January 10, 2014

Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants.

Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants.

Journal: BMC medical genomics
Published: September 05, 2012

Characterization of the melanocortin-4-receptor nonsense mutation W16X in vitro and in vivo.

Characterization of the melanocortin-4-receptor nonsense mutation W16X in vitro and in vivo.

Journal: The pharmacogenomics journal
Published: October 05, 2011
Showing 1-12 of 13

Last Updated: 09/26/2026