Florian Le Joubioux
Valbiotis R&D
La Rochelle, 17000, France
La Rochelle, 17000, France
Last Updated: 09/26/2026
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Found 15 publications
Depolymerized fucoidan derivatives anti-migratory activity, driven by structure-controlled uptake, overrides heparanase in breast cancer cells.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: May 29, 2026
Bioavailable human metabolites from TOTUM-448 (plant-based formulation) maintain liver cell functionality in a hyperlipidic context that drives MASLD onset.
Journal: Scientific reports
Published: August 26, 2025
Totum-448 Improves MASLD and Modulates Microbiota in Hamsters: Dose-Response Study and Effects of Supplementation Cessation.
Journal: Food science & nutrition
Published: May 06, 2025
Totum-63, a plant-based polyphenol-rich extract, in prediabetes or early-stage type 2 diabetes: an international, multicenter, randomized controlled trial.
Journal: Nature communications
Published: March 20, 2025
Effect of a polyphenol-rich extract on LDL cholesterol in mild to moderate hypercholesterolemia: a randomized, double-blind, placebo-controlled trial.
Journal: European journal of clinical nutrition
Published: February 14, 2025
TOTUM-854 Human Circulating Bioactives Preserve Endothelial Cell Function.
Journal: Nutrients
Published: January 28, 2025
A polyphenol-rich plant extract prevents hypercholesterolemia and modulates gut microbiota in western diet-fed mice.
Journal: Frontiers in cardiovascular medicine
Published: November 21, 2023
Totum-070, a Polyphenol-Rich Plant Extract, Prevents Hypercholesterolemia in High-Fat Diet-Fed Hamsters by Inhibiting Intestinal Cholesterol Absorption.
Journal: Nutrients
Published: November 03, 2023
Inhibitory Potential of α-Amylase, α-Glucosidase, and Pancreatic Lipase by a Formulation of Five Plant Extracts: TOTUM-63.
Journal: International journal of molecular sciences
Published: January 18, 2023
TOTUM-63, a plant-based polyphenol-rich extract, improves glycaemic control in subjects with prediabetes or early stage newly-diagnosed type 2 diabetes in a randomized, double-blind, placebo-controlled trial.
Journal: Diabetes, obesity & metabolism
Published: February 06, 2022
Impact of TOTUM-63, a fibre and polyphenol rich plant-based composition, on gut and pancreatic hormone secretion in diet-induced obese mice.
Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD
Published: December 14, 2021
Effects of Totum-63 on glucose homeostasis and postprandial glycemia: a translational study.
Journal: American journal of physiology. Endocrinology and metabolism
Published: May 03, 2021
Last Updated: 09/26/2026