Florian Perner

Hannover, NI, Germany

Last Updated: 09/26/2026

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Found 47 publications

A novel role for transcription factor NFE2 in redox regulation and chemotherapy resistance in acute myeloid leukemia.

A novel role for transcription factor NFE2 in redox regulation and chemotherapy resistance in acute myeloid leukemia.

Journal: Leukemia
Published: February 23, 2026

Menin-MLL inhibitors enhance JUND activity in MLLr leukemic cells contributing to tumorigenesis and therapy resistance.

Menin-MLL inhibitors enhance JUND activity in MLLr leukemic cells contributing to tumorigenesis and therapy resistance.

Journal: Blood
Published: November 07, 2025

USP22 is a novel vulnerability regulating MEIS1 protein abundance and gene transcription in KMT2Ar acute leukemia.

USP22 is a novel vulnerability regulating MEIS1 protein abundance and gene transcription in KMT2Ar acute leukemia.

Journal: Blood
Published: September 29, 2025

Lysine-specific demethylase 1 regulates hematopoietic stem cell expansion and myeloid cell differentiation.

Lysine-specific demethylase 1 regulates hematopoietic stem cell expansion and myeloid cell differentiation.

Journal: Cell death & disease
Published: June 12, 2025

Menin inhibition enhances graft-versus-leukemia effects by T-cell activation and endogenous retrovirus induction in AML.

Menin inhibition enhances graft-versus-leukemia effects by T-cell activation and endogenous retrovirus induction in AML.

Journal: Blood
Published: April 24, 2025

CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trials.

CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trials.

Journal: Nature communications
Published: March 28, 2025

The histone-methyltransferase DOT1L cooperates with LSD1 to control cell division in blast-phase MPN.

The histone-methyltransferase DOT1L cooperates with LSD1 to control cell division in blast-phase MPN.

Journal: Leukemia
Published: January 06, 2025

Malignant JAK-signaling: at the interface of inflammation and malignant transformation.

Malignant JAK-signaling: at the interface of inflammation and malignant transformation.

Journal: Leukemia
Published: January 02, 2025

Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia.

Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia.

Journal: bioRxiv : the preprint server for biology
Published: December 23, 2024

Targeting the Menin-KMT2A interaction in leukemia: Lessons learned and future directions.

Targeting the Menin-KMT2A interaction in leukemia: Lessons learned and future directions.

Journal: International journal of cancer
Published: November 25, 2024

Therapeutic targeting of chromatin alterations in leukemia and solid tumors.

Therapeutic targeting of chromatin alterations in leukemia and solid tumors.

Journal: International journal of cancer
Published: November 25, 2024

Catalytic Inhibition of KAT6/KAT7 Enhances the Efficacy and Overcomes Primary and Acquired Resistance to Menin Inhibitors in MLL Leukemia.

Catalytic Inhibition of KAT6/KAT7 Enhances the Efficacy and Overcomes Primary and Acquired Resistance to Menin Inhibitors in MLL Leukemia.

Journal: Cancer discovery
Published: October 22, 2024
Showing 1-12 of 47

Last Updated: 09/26/2026