Frances A. Edwards
Gower Street
London, ENG, United Kingdom
London, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 21 publications
Isotope Encoded Spatial Biology Identifies Amyloid Plaque-Age-Dependent Structural Maturation, Synaptic Loss, and Increased Toxicity.
Journal: Research square
Published: February 20, 2025
Isotope-encoded spatial biology identifies plaque-age-dependent maturation and synaptic loss in an Alzheimer's disease mouse model.
Journal: Nature communications
Published: January 14, 2025
Age- and amyloid-β-dependent initiation of neurofibrillary tau tangles: an improved mouse model of Alzheimer's disease without mutations in MAPT.
Journal: bioRxiv : the preprint server for biology
Published: November 22, 2024
Isotope Encoded chemical Imaging Identifies Amyloid Plaque Age Dependent Structural Maturation, Synaptic Loss, and Increased Toxicity.
Journal: bioRxiv : the preprint server for biology
Published: October 17, 2024
Plaque contact and unimpaired Trem2 is required for the microglial response to amyloid pathology.
Journal: Cell reports
Published: February 22, 2022
Following spatial Aβ aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics.
Journal: Science advances
Published: January 11, 2021
Prodromal neuroinflammatory, cholinergic and metabolite dysfunction detected by PET and MRS in the TgF344-AD transgenic rat model of AD: a collaborative multi-modal study.
Journal: Theranostics
Published: November 17, 2020
Knock-in models related to Alzheimer's disease: synaptic transmission, plaques and the role of microglia.
Journal: Molecular neurodegeneration
Published: October 21, 2020
Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions.
Journal: Human molecular genetics
Published: June 24, 2020
Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment.
Journal: Human molecular genetics
Published: August 30, 2019
Clinical characteristics and treatment outcomes in a cohort of patients with pyogenic and amoebic liver abscess.
Journal: BMC infectious diseases
Published: February 13, 2019
Improving Mouse Models for Dementia. Are All the Effects in Tau Mouse Models Due to Overexpression?
Journal: Cold Spring Harbor symposia on quantitative biology
Published: February 13, 2019
Last Updated: 09/26/2026