Francesca Clemente

Via Della Lastruccia 3-13, FI
Sesto Fiorentino, 50019, Italy

Last Updated: 09/26/2026

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Found 26 publications

Carbohydrate- and heterocycle-based β-glucocerebrosidase inhibitors: State of the art and emerging relationship with cancer treatment.

Carbohydrate- and heterocycle-based β-glucocerebrosidase inhibitors: State of the art and emerging relationship with cancer treatment.

Journal: European journal of medicinal chemistry

Published: May 08, 2026

Multivalent C2-alkyl trihydroxypiperidine architectures modulate β-glucocerebrosidase activity.

Multivalent C2-alkyl trihydroxypiperidine architectures modulate β-glucocerebrosidase activity.

Journal: European journal of medicinal chemistry

Published: March 31, 2026

Selenoureido-N-alkyl-3,4,5-trihydroxypiperidines: probing their dual-target role in Gaucher disease.

Selenoureido-N-alkyl-3,4,5-trihydroxypiperidines: probing their dual-target role in Gaucher disease.

Journal: Bioorganic & medicinal chemistry

Published: July 31, 2025

Simultaneous Grafting of 3,4,5-Trihydroxypiperidine Iminosugars Onto Multivalent Scaffolds via Double Reductive Amination Provides New GCase Inhibitors.

Simultaneous Grafting of 3,4,5-Trihydroxypiperidine Iminosugars Onto Multivalent Scaffolds via Double Reductive Amination Provides New GCase Inhibitors.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: July 31, 2025

Molecular Basis of Pseudomonas syringae pv actinidiae Levansucrase Inhibition by a Multivalent Iminosugar.

Molecular Basis of Pseudomonas syringae pv actinidiae Levansucrase Inhibition by a Multivalent Iminosugar.

Journal: Journal of agricultural and food chemistry

Published: May 11, 2025

Exploring Multivalent Architectures for Binding and Stabilization of N-Acetylgalactosamine 6-Sulfatase.

Exploring Multivalent Architectures for Binding and Stabilization of N-Acetylgalactosamine 6-Sulfatase.

Journal: Molecules (Basel, Switzerland)

Published: March 31, 2025

Evidence of α-Synuclein/Glucocerebrosidase Dual Targeting by Iminosugar Derivatives.

Evidence of α-Synuclein/Glucocerebrosidase Dual Targeting by Iminosugar Derivatives.

Journal: ACS chemical neuroscience

Published: March 13, 2025

Acetal functionalized iminosugars for targeting β-glucocerebrosidase modulation.

Acetal functionalized iminosugars for targeting β-glucocerebrosidase modulation.

Journal: European journal of medicinal chemistry

Published: December 27, 2024

Multivalent GCase Enhancers: Synthesis and Evaluation of Glyco-Gold Nanoparticles Decorated with Trihydroxypiperidine Iminosugars.

Multivalent GCase Enhancers: Synthesis and Evaluation of Glyco-Gold Nanoparticles Decorated with Trihydroxypiperidine Iminosugars.

Journal: Bioconjugate chemistry

Published: December 19, 2024

Iminosugar-Dihydroazulenes as Mutant L444P Glucocerebrosidase Enhancers.

Iminosugar-Dihydroazulenes as Mutant L444P Glucocerebrosidase Enhancers.

Journal: Chemistry & biodiversity

Published: May 06, 2024

Identification of GM1-Ganglioside Secondary Accumulation in Fibroblasts from Neuropathic Gaucher Patients and Effect of a Trivalent Trihydroxypiperidine Iminosugar Compound on Its Storage Reduction.

Identification of GM1-Ganglioside Secondary Accumulation in Fibroblasts from Neuropathic Gaucher Patients and Effect of a Trivalent Trihydroxypiperidine Iminosugar Compound on Its Storage Reduction.

Journal: Molecules (Basel, Switzerland)

Published: December 22, 2023

Gold nanoparticles decorated with monosaccharides and sulfated ligands as potential modulators of the lysosomal enzyme N-acetylgalactosamine-6-sulfatase (GALNS).

Gold nanoparticles decorated with monosaccharides and sulfated ligands as potential modulators of the lysosomal enzyme N-acetylgalactosamine-6-sulfatase (GALNS).

Journal: Organic & biomolecular chemistry

Published: November 17, 2023

Showing 1-12 of 26

Last Updated: 09/26/2026