Francesca Seghetti

Via Belmeloro 6
Bologna, 40126, Italy

Last Updated: 09/26/2026

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Found 16 publications

Exploiting acylaminopyrazole scaffold for polypharmacology approach in Alzheimer's disease.

Exploiting acylaminopyrazole scaffold for polypharmacology approach in Alzheimer's disease.

Journal: European journal of medicinal chemistry

Published: March 19, 2025

Alkyl Tail Variation on Chalcone-Based Quaternary Pyridinium Salts as Rule-of-Thumb for Antimicrobial Activity.

Alkyl Tail Variation on Chalcone-Based Quaternary Pyridinium Salts as Rule-of-Thumb for Antimicrobial Activity.

Journal: Archiv der Pharmazie

Published: October 21, 2024

Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis.

Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis.

Journal: Journal of medicinal chemistry

Published: January 02, 2024

Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold.

Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold.

Journal: European journal of medicinal chemistry

Published: January 30, 2023

Hitting drug-resistant malaria infection with triazole-linked flavonoid-chloroquine hybrid compounds.

Hitting drug-resistant malaria infection with triazole-linked flavonoid-chloroquine hybrid compounds.

Journal: Future medicinal chemistry

Published: January 09, 2023

Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One.

Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One.

Journal: Journal of medicinal chemistry

Published: July 11, 2022

Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design.

Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design.

Journal: Frontiers in molecular biosciences

Published: March 21, 2022

Modulation of Amyloid β-Induced Microglia Activation and Neuronal Cell Death by Curcumin and Analogues.

Modulation of Amyloid β-Induced Microglia Activation and Neuronal Cell Death by Curcumin and Analogues.

Journal: International journal of molecular sciences

Published: March 08, 2022

Interplay Between Endocannabinoid System and Neurodegeneration: Focus on Polypharmacology.

Interplay Between Endocannabinoid System and Neurodegeneration: Focus on Polypharmacology.

Journal: Current medicinal chemistry

Published: August 05, 2021

Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease.

Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease.

Journal: ACS chemical neuroscience

Published: July 15, 2020

Curcumin-1,2,3-Triazole Conjugation for Targeting the Cancer Apoptosis Machinery.

Curcumin-1,2,3-Triazole Conjugation for Targeting the Cancer Apoptosis Machinery.

Journal: Molecules (Basel, Switzerland)

Published: May 27, 2020

Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation.

Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation.

Journal: ChemMedChem

Published: April 03, 2020

Showing 1-12 of 16

Last Updated: 09/26/2026