Francesco Manfredi

Milan, Italy

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 14 publications

The longitudinal characterization of immune responses in COVID-19 patients reveals novel prognostic signatures for disease severity, patients' survival and long COVID.

The longitudinal characterization of immune responses in COVID-19 patients reveals novel prognostic signatures for disease severity, patients' survival and long COVID.

Journal: Frontiers in immunology

Published: February 02, 2024

Harnessing T cell exhaustion and trogocytosis to isolate patient-derived tumor-specific TCR.

Harnessing T cell exhaustion and trogocytosis to isolate patient-derived tumor-specific TCR.

Journal: Science advances

Published: December 01, 2023

TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells.

TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells.

Journal: Frontiers in immunology

Published: October 10, 2023

Epithelial ovarian cancer is infiltrated by activated effector T cells co-expressing CD39, PD-1, TIM-3, CD137 and interacting with cancer cells and myeloid cells.

Epithelial ovarian cancer is infiltrated by activated effector T cells co-expressing CD39, PD-1, TIM-3, CD137 and interacting with cancer cells and myeloid cells.

Journal: Frontiers in immunology

Published: April 26, 2023

Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells.

Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells.

Journal: Gut

Published: June 14, 2022

CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function.

CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function.

Journal: Science translational medicine

Published: February 09, 2022

Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies.

Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies.

Journal: Science translational medicine

Published: January 19, 2022

Cytomegalovirus-specific T cells restricted for shared and donor human leukocyte antigens differentially impact on cytomegalovirus reactivation risk after allogeneic hematopoietic stem cell transplantation.

Cytomegalovirus-specific T cells restricted for shared and donor human leukocyte antigens differentially impact on cytomegalovirus reactivation risk after allogeneic hematopoietic stem cell transplantation.

Journal: Haematologica

Published: January 18, 2022

Workflow for high-dimensional flow cytometry analysis of T cells from tumor metastases.

Workflow for high-dimensional flow cytometry analysis of T cells from tumor metastases.

Journal: Life science alliance

Published: November 24, 2021

CAR T cell manufacturing from naive/stem memory T lymphocytes enhances antitumor responses while curtailing cytokine release syndrome.

CAR T cell manufacturing from naive/stem memory T lymphocytes enhances antitumor responses while curtailing cytokine release syndrome.

Journal: The Journal of clinical investigation

Published: April 23, 2021

Flow cytometry data mining by cytoChain identifies determinants of exhaustion and stemness in TCR-engineered T cells.

Flow cytometry data mining by cytoChain identifies determinants of exhaustion and stemness in TCR-engineered T cells.

Journal: European journal of immunology

Published: December 03, 2020

TCR Redirected T Cells for Cancer Treatment: Achievements, Hurdles, and Goals.

TCR Redirected T Cells for Cancer Treatment: Achievements, Hurdles, and Goals.

Journal: Frontiers in immunology

Published: April 08, 2020

Showing 1-12 of 14

Last Updated: 09/26/2026