Francesco Melfi

Chieti, 66100, Italy

Last Updated: 09/26/2026

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Found 19 publications

Coumarin- and Dipicolylamine-Terpenoid Hybrids as Selective Carbonic Anhydrases IX and XII Inhibitors: Mechanistic Insights and Selective Anti-Cancer Potential.

Coumarin- and Dipicolylamine-Terpenoid Hybrids as Selective Carbonic Anhydrases IX and XII Inhibitors: Mechanistic Insights and Selective Anti-Cancer Potential.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: March 31, 2026

Hybridization Approach Applied to Umbelliferon and Vanilloids toward New Inhibitors of Carbonic Anhydrases IX and XII with In Vitro Antiproliferative and Anti-inflammatory Activities.

Hybridization Approach Applied to Umbelliferon and Vanilloids toward New Inhibitors of Carbonic Anhydrases IX and XII with In Vitro Antiproliferative and Anti-inflammatory Activities.

Journal: Journal of medicinal chemistry

Published: January 08, 2026

An Agonist/Antagonist Photo-Switchable Vitamin D Mimetic Enables Bidirectional Optical Control of VDR.

An Agonist/Antagonist Photo-Switchable Vitamin D Mimetic Enables Bidirectional Optical Control of VDR.

Journal: Angewandte Chemie (International ed. in English)

Published: December 29, 2025

Phenolic terpenes in liposomal bilayers: Unraveling physicochemical interactions and membrane perturbation via biophysical and computational approaches.

Phenolic terpenes in liposomal bilayers: Unraveling physicochemical interactions and membrane perturbation via biophysical and computational approaches.

Journal: Journal of colloid and interface science

Published: April 10, 2025

O-derivatization of natural tropolone and β-thujaplicin leading to effective inhibitors of human carbonic anhydrases IX and XII.

O-derivatization of natural tropolone and β-thujaplicin leading to effective inhibitors of human carbonic anhydrases IX and XII.

Journal: European journal of medicinal chemistry

Published: February 18, 2025

Potential of MAO-B Inhibitors with Multi-Target Inhibition and Antioxidant Properties for the Treatment of Neurodegenerative Disorders.

Potential of MAO-B Inhibitors with Multi-Target Inhibition and Antioxidant Properties for the Treatment of Neurodegenerative Disorders.

Journal: Mini reviews in medicinal chemistry

Published: February 12, 2025

Potential of MAO-B Inhibitors with Multi-target Inhibition and Antioxidant Properties for the Treatment of Neurodegenerative Disorders.

Potential of MAO-B Inhibitors with Multi-target Inhibition and Antioxidant Properties for the Treatment of Neurodegenerative Disorders.

Journal: Mini reviews in medicinal chemistry

Published: February 12, 2025

Inhibition of Pseudomonas aeruginosa Carbonic Anhydrases, Exploring Ciprofloxacin Functionalization Toward New Antibacterial Agents: An In-Depth Multidisciplinary Study.

Inhibition of Pseudomonas aeruginosa Carbonic Anhydrases, Exploring Ciprofloxacin Functionalization Toward New Antibacterial Agents: An In-Depth Multidisciplinary Study.

Journal: Journal of medicinal chemistry

Published: October 25, 2024

Drug design of tyrosinase inhibitors.

Drug design of tyrosinase inhibitors.

Journal: The Enzymes

Published: September 20, 2024

Design, Synthesis, Molecular Modeling and Biological Evaluation of Novel Benzothiazole-Based 1,3,4-Thiadiazole Derivatives as Potential Anticancer Agents.

Design, Synthesis, Molecular Modeling and Biological Evaluation of Novel Benzothiazole-Based 1,3,4-Thiadiazole Derivatives as Potential Anticancer Agents.

Journal: Anti-cancer agents in medicinal chemistry

Published: August 26, 2024

Azo derivatives of monoterpenes as anti-Helicobacter pylori agents: from synthesis to structure-based target investigation.

Azo derivatives of monoterpenes as anti-Helicobacter pylori agents: from synthesis to structure-based target investigation.

Journal: RSC medicinal chemistry

Published: July 07, 2024

Fine-tuning of membrane permeability by reversible photoisomerization of aryl-azo derivatives of thymol embedded in lipid nanoparticles.

Fine-tuning of membrane permeability by reversible photoisomerization of aryl-azo derivatives of thymol embedded in lipid nanoparticles.

Journal: Colloids and surfaces. B, Biointerfaces

Published: March 14, 2024

Showing 1-12 of 19

Last Updated: 09/26/2026