Francesco Merlino

Via Domenico Montesano 49 80131
Naples, 80131, Italy

Last Updated: 09/26/2026

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Found 67 publications

Goldilocks-Inspired Design of Mid-Size Macrocycles for Selective Targeting of Human Melanocortin Receptors.

Goldilocks-Inspired Design of Mid-Size Macrocycles for Selective Targeting of Human Melanocortin Receptors.

Journal: Journal of medicinal chemistry
Published: June 24, 2026

Chemical Optimization of Temporin A-L Peptides: From Native Isoforms to Enhanced Antimicrobial Analogs.

Chemical Optimization of Temporin A-L Peptides: From Native Isoforms to Enhanced Antimicrobial Analogs.

Journal: ChemMedChem
Published: May 14, 2026

Coupling PD-L1 Inhibition and Lysosomal Degradation: Innovative Anti-PD-L1 Peptides for NSCLC Immunotherapy.

Coupling PD-L1 Inhibition and Lysosomal Degradation: Innovative Anti-PD-L1 Peptides for NSCLC Immunotherapy.

Journal: Journal of medicinal chemistry
Published: February 23, 2026

Structure-Guided Design of Temporin-Derived Peptides Reveals Potent Dual-Mechanism Inhibitors of SARS-CoV-2.

Structure-Guided Design of Temporin-Derived Peptides Reveals Potent Dual-Mechanism Inhibitors of SARS-CoV-2.

Journal: Journal of medicinal chemistry
Published: February 02, 2026

Probing Guanidino Pendant or Bridged Groups in Cyclic Antimicrobial Peptides Derived from Temporin L: A Strategy to Improve Efficacy against Gram-Negative Bacteria.

Probing Guanidino Pendant or Bridged Groups in Cyclic Antimicrobial Peptides Derived from Temporin L: A Strategy to Improve Efficacy against Gram-Negative Bacteria.

Journal: Journal of medicinal chemistry
Published: December 01, 2025

Harnessing red grape pomace extract for sustainable broad-spectrum photoprotection in a reconstructed human epidermis model.

Harnessing red grape pomace extract for sustainable broad-spectrum photoprotection in a reconstructed human epidermis model.

Journal: Frontiers in pharmacology
Published: November 11, 2025

Design and evaluation of dual-functional aptamer-peptide conjugates as a platform for targeted cancer therapy.

Design and evaluation of dual-functional aptamer-peptide conjugates as a platform for targeted cancer therapy.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Published: November 06, 2025

Unveiling the biological effects of DNA G-quadruplex ligands through multi-omics data integration.

Unveiling the biological effects of DNA G-quadruplex ligands through multi-omics data integration.

Journal: International journal of biological macromolecules
Published: February 03, 2025

Sustainable Ultrasound-Assisted Solid-Phase peptide synthesis (SUS-SPPS): Less Waste, more efficiency.

Sustainable Ultrasound-Assisted Solid-Phase peptide synthesis (SUS-SPPS): Less Waste, more efficiency.

Journal: Ultrasonics sonochemistry
Published: December 02, 2024

Glioblastoma Cell Migration, Invasion and Vasculogenic Mimicry Downmodulated by Novel uPAcyclin Derivatives.

Glioblastoma Cell Migration, Invasion and Vasculogenic Mimicry Downmodulated by Novel uPAcyclin Derivatives.

Journal: Cells
Published: November 27, 2024

Expanding Structure-Activity Relationships of Human Urotensin II Peptide Analogues: A Proposed Key Role of the N-Terminal Region for Novel Urotensin II Receptor Modulators.

Expanding Structure-Activity Relationships of Human Urotensin II Peptide Analogues: A Proposed Key Role of the N-Terminal Region for Novel Urotensin II Receptor Modulators.

Journal: Journal of medicinal chemistry
Published: August 03, 2024

Sensitization of melanoma cells to standard chemotherapy: G-quadruplex binders as synergistic agents.

Sensitization of melanoma cells to standard chemotherapy: G-quadruplex binders as synergistic agents.

Journal: NAR cancer
Published: July 27, 2024
Showing 1-12 of 67

Last Updated: 09/26/2026