Francis K. Chiu

Parkville, VIC 3052, Australia

Last Updated: 09/26/2026

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Found 17 publications

Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials.

Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials.

Journal: Journal of medicinal chemistry

Published: August 26, 2021

Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439.

Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439.

Journal: ACS infectious diseases

Published: June 08, 2021

Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria.

Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria.

Journal: Journal of medicinal chemistry

Published: April 07, 2020

Structure-Activity Relationship of Antischistosomal Ozonide Carboxylic Acids.

Structure-Activity Relationship of Antischistosomal Ozonide Carboxylic Acids.

Journal: Journal of medicinal chemistry

Published: March 06, 2020

An in vitro toolbox to accelerate anti-malarial drug discovery and development.

An in vitro toolbox to accelerate anti-malarial drug discovery and development.

Journal: Malaria journal

Published: August 11, 2019

Potential Diagnostic Imaging of Alzheimer's Disease with Copper-64 Complexes That Bind to Amyloid-β Plaques.

Potential Diagnostic Imaging of Alzheimer's Disease with Copper-64 Complexes That Bind to Amyloid-β Plaques.

Journal: Inorganic chemistry

Published: February 21, 2019

3,3'-Disubstituted 5,5'-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity.

3,3'-Disubstituted 5,5'-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity.

Journal: Journal of medicinal chemistry

Published: February 05, 2019

Using Human Plasma as an Assay Medium in Caco-2 Studies Improves Mass Balance for Lipophilic Compounds.

Using Human Plasma as an Assay Medium in Caco-2 Studies Improves Mass Balance for Lipophilic Compounds.

Journal: Pharmaceutical research

Published: March 26, 2018

Structure-Activity Relationship of the Antimalarial Ozonide Artefenomel (OZ439).

Structure-Activity Relationship of the Antimalarial Ozonide Artefenomel (OZ439).

Journal: Journal of medicinal chemistry

Published: January 05, 2017

Revisiting the SAR of the Antischistosomal Aryl Hydantoin (Ro 13-3978).

Revisiting the SAR of the Antischistosomal Aryl Hydantoin (Ro 13-3978).

Journal: Journal of medicinal chemistry

Published: December 10, 2016

A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria.

A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria.

Journal: ACS infectious diseases

Published: September 20, 2016

Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism.

Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism.

Journal: Journal of medicinal chemistry

Published: March 11, 2016

Showing 1-12 of 17

Last Updated: 09/26/2026