Francisco B. Mendonca-Junior

Joao Pessoa, PB 58051900, Brazil

Last Updated: 09/26/2026

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Found 96 publications

Guanidines: Privileged Scaffolds Against Neglected Tropical Diseases: A Review.

Guanidines: Privileged Scaffolds Against Neglected Tropical Diseases: A Review.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: April 09, 2026

Inhibitory effects of thiophene-2-thiazole hybrids against sensitive strains and resistant clinical isolates of Mycobacterium tuberculosis.

Inhibitory effects of thiophene-2-thiazole hybrids against sensitive strains and resistant clinical isolates of Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters

Published: March 06, 2026

Insights into a new class of antileishmanial compounds: an in vitro and in silico study of 1,2,4-oxadiazol-5(4H)-one derivatives.

Insights into a new class of antileishmanial compounds: an in vitro and in silico study of 1,2,4-oxadiazol-5(4H)-one derivatives.

Journal: Bioorganic chemistry

Published: January 28, 2026

5,6,7,8-Tetrahydroimidazo[1,2-a]pyrazine-based thiosemicarbazones as anti-Trypanosoma cruzi agents.

5,6,7,8-Tetrahydroimidazo[1,2-a]pyrazine-based thiosemicarbazones as anti-Trypanosoma cruzi agents.

Journal: Bioorganic & medicinal chemistry

Published: January 24, 2026

QSAR-based drug discovery of 2-((4-Imino-3,4-dihydroquinazolin-2-yl)thio-substituted analogs targeting Mycobacterium tuberculosis.

QSAR-based drug discovery of 2-((4-Imino-3,4-dihydroquinazolin-2-yl)thio-substituted analogs targeting Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry

Published: December 15, 2025

Advances in leishmaniasis therapy: preparation, characterization and in vitro evaluation of poly (lactic acid) polymeric nanoparticles with the drug candidate SB-83.

Advances in leishmaniasis therapy: preparation, characterization and in vitro evaluation of poly (lactic acid) polymeric nanoparticles with the drug candidate SB-83.

Journal: Nanotechnology

Published: December 09, 2025

Nanostructured Lipid Carriers Containing Norfloxacin and 2-Aminothiophene Derivative Reduces Fluoroquinolone Resistance in Multidrug-Resistant Staphylococcus aureus Strains by Efflux Pump Inhibition.

Nanostructured Lipid Carriers Containing Norfloxacin and 2-Aminothiophene Derivative Reduces Fluoroquinolone Resistance in Multidrug-Resistant Staphylococcus aureus Strains by Efflux Pump Inhibition.

Journal: Pharmaceutics

Published: December 07, 2025

2-Aminothiophene Derivative SB-83 Inhibits Trypanothione Reductase and Modulates Cytokine Production in Trypanosoma cruzi-Infected Cells.

2-Aminothiophene Derivative SB-83 Inhibits Trypanothione Reductase and Modulates Cytokine Production in Trypanosoma cruzi-Infected Cells.

Journal: Pathogens (Basel, Switzerland)

Published: November 28, 2025

In vitro and in vivo efficacy of PI3Kγ inhibitor AS605240 in controlling mycobacterial infections.

In vitro and in vivo efficacy of PI3Kγ inhibitor AS605240 in controlling mycobacterial infections.

Journal: Tuberculosis (Edinburgh, Scotland)

Published: August 07, 2025

Drug design and synthesis of new N-substituted-thienopyridine based on 2-aminothiophene derivatives as antileishmanial agents.

Drug design and synthesis of new N-substituted-thienopyridine based on 2-aminothiophene derivatives as antileishmanial agents.

Journal: Bioorganic & medicinal chemistry

Published: August 04, 2025

2-Aminothiophene derivatives reduce resistance to fluoroquinolones in Staphylococcus aureus strains which overexpress NorA and MepA efflux pumps.

2-Aminothiophene derivatives reduce resistance to fluoroquinolones in Staphylococcus aureus strains which overexpress NorA and MepA efflux pumps.

Journal: Biochimie

Published: May 12, 2025

FERAI, a novel brominated chalcone, induces ultrastructural alterations and apoptosis like-death in Leishmania braziliensis.

FERAI, a novel brominated chalcone, induces ultrastructural alterations and apoptosis like-death in Leishmania braziliensis.

Journal: Acta tropica

Published: May 05, 2025

Showing 1-12 of 96

Last Updated: 09/26/2026