Francisco J. Areales-Perez

Barcelona, CT 08028, Spain

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 13 publications

Targeting a Pleckstrin Homology Domain with a Lysine-Reactive Covalent Binder.

Targeting a Pleckstrin Homology Domain with a Lysine-Reactive Covalent Binder.

Journal: Journal of medicinal chemistry

Published: May 14, 2026

Towards a glutathione-cleavable azobenzene linker for antibody-drug conjugates.

Towards a glutathione-cleavable azobenzene linker for antibody-drug conjugates.

Journal: Chemical communications (Cambridge, England)

Published: November 05, 2025

Stepwise Structural Simplification of the Dihydroxyanthraquinone Moiety of a Multitarget Rhein-Based Anti-Alzheimer Lead to Improve Drug Metabolism and Pharmacokinetic Properties.

Stepwise Structural Simplification of the Dihydroxyanthraquinone Moiety of a Multitarget Rhein-Based Anti-Alzheimer Lead to Improve Drug Metabolism and Pharmacokinetic Properties.

Journal: Pharmaceutics

Published: June 26, 2024

Towards the Targeted Protein Degradation of PRMT1.

Towards the Targeted Protein Degradation of PRMT1.

Journal: ChemMedChem

Published: April 15, 2024

Red-light modulated ortho-chloro azobenzene photoswitch for peptide stapling via aromatic substitution.

Red-light modulated ortho-chloro azobenzene photoswitch for peptide stapling via aromatic substitution.

Journal: RSC chemical biology

Published: September 18, 2023

Hybrid Androgen Receptor Inhibitors Outperform Enzalutamide and EPI-001 in in vitro Models of Prostate Cancer Drug Resistance.

Hybrid Androgen Receptor Inhibitors Outperform Enzalutamide and EPI-001 in in vitro Models of Prostate Cancer Drug Resistance.

Journal: ChemMedChem

Published: October 10, 2022

Unveiling the Multitarget Anti-Alzheimer Drug Discovery Landscape: A Bibliometric Analysis.

Unveiling the Multitarget Anti-Alzheimer Drug Discovery Landscape: A Bibliometric Analysis.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: March 11, 2022

Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6.

Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6.

Journal: Journal of medicinal chemistry

Published: July 25, 2020

A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.

A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.

Journal: European journal of medicinal chemistry

Published: March 27, 2019

Design, synthesis and multitarget biological profiling of second-generation anti-Alzheimer rhein-huprine hybrids.

Design, synthesis and multitarget biological profiling of second-generation anti-Alzheimer rhein-huprine hybrids.

Journal: Future medicinal chemistry

Published: June 21, 2017

Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.

Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.

Journal: Bioorganic & medicinal chemistry

Published: July 13, 2016

Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties.

Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties.

Journal: Bioorganic & medicinal chemistry

Published: June 27, 2014

Showing 1-12 of 13

Last Updated: 09/26/2026