Frank Buchholz

Dresden, SN, Germany

Last Updated: 09/26/2026

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Found 105 publications

Restoring Cancer Genomes: Functional Mutation Correction as a Platform for Precision Oncology.

Restoring Cancer Genomes: Functional Mutation Correction as a Platform for Precision Oncology.

Journal: Human gene therapy
Published: July 27, 2026

A retargeted recombinase for precise insertion of large DNA.

A retargeted recombinase for precise insertion of large DNA.

Journal: Nature biotechnology
Published: June 29, 2026

INSTALLing recombinase-driven genome writing: Engineered single-stranded donors bypass innate immunity to enable large DNA integration.

INSTALLing recombinase-driven genome writing: Engineered single-stranded donors bypass innate immunity to enable large DNA integration.

Journal: Molecular cell
Published: April 20, 2026

Epigenetic editing balances TCR suppression and persistence in CAR T cells.

Epigenetic editing balances TCR suppression and persistence in CAR T cells.

Journal: Molecular therapy. Advances
Published: September 03, 2025

Knock Out of miRNA-30a-5p and Reconstitution of the Actin Network Dynamics Partly Restores the Impaired Terminal Erythroid Differentiation during Blood Pharming.

Knock Out of miRNA-30a-5p and Reconstitution of the Actin Network Dynamics Partly Restores the Impaired Terminal Erythroid Differentiation during Blood Pharming.

Journal: Stem cell reviews and reports
Published: July 27, 2025

NCBP2-AS2 is a mitochondrial microprotein, regulates energy metabolism and neurogenesis, and is downregulated in Alzheimer's disease.

NCBP2-AS2 is a mitochondrial microprotein, regulates energy metabolism and neurogenesis, and is downregulated in Alzheimer's disease.

Journal: bioRxiv : the preprint server for biology
Published: February 20, 2025

A base editing platform for the correction of cancer driver mutations unmasks conserved p53 transcription programs.

A base editing platform for the correction of cancer driver mutations unmasks conserved p53 transcription programs.

Journal: Genome biology
Published: February 07, 2025

A pooled CRISPR screen identifies the Tα2 enhancer element as a driver of TRA expression in a subset of mature human T lymphocytes.

A pooled CRISPR screen identifies the Tα2 enhancer element as a driver of TRA expression in a subset of mature human T lymphocytes.

Journal: Frontiers in immunology
Published: November 28, 2024

Methylstat sensitizes ovarian cancer cells to PARP-inhibition by targeting the histone demethylases JMJD1B/C.

Methylstat sensitizes ovarian cancer cells to PARP-inhibition by targeting the histone demethylases JMJD1B/C.

Journal: Cancer gene therapy
Published: August 30, 2024

Selective regulation of aspartyl intramembrane protease activity by calnexin.

Selective regulation of aspartyl intramembrane protease activity by calnexin.

Journal: Cellular and molecular life sciences : CMLS
Published: June 12, 2024

The histone modifier KAT2A presents a selective target in a subset of well-differentiated microsatellite-stable colorectal cancers.

The histone modifier KAT2A presents a selective target in a subset of well-differentiated microsatellite-stable colorectal cancers.

Journal: Cell death and differentiation
Published: June 07, 2024

Characterization of immortalized bone marrow erythroid progenitor adult (imBMEP-A)-The first inducible immortalized red blood cell progenitor cell line derived from bone marrow CD71-positive cells.

Characterization of immortalized bone marrow erythroid progenitor adult (imBMEP-A)-The first inducible immortalized red blood cell progenitor cell line derived from bone marrow CD71-positive cells.

Journal: Cytotherapy
Published: February 28, 2024
Showing 1-12 of 105

Last Updated: 09/26/2026