Frank G. Jacobs

Janssen R&D
Beerse, VLG, Belgium

Last Updated: 09/26/2026

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Found 34 publications

Renewable energy caves: water replenishment holes in offshore monopiles create novel marine habitats.

Renewable energy caves: water replenishment holes in offshore monopiles create novel marine habitats.

Journal: Journal of environmental management
Published: June 03, 2026

DMPK Considerations for the Development of Covalent Drugs: Insights from an IQ Assessment.

DMPK Considerations for the Development of Covalent Drugs: Insights from an IQ Assessment.

Journal: Journal of medicinal chemistry
Published: April 28, 2026

A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein.

A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein.

Journal: Nature
Published: February 21, 2024

Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias.

Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias.

Journal: Blood
Published: September 12, 2023

Interlaboratory Variability in the Madin-Darby Canine Kidney Cell Proteome.

Interlaboratory Variability in the Madin-Darby Canine Kidney Cell Proteome.

Journal: Molecular pharmaceutics
Published: June 07, 2023

Correction to: Clinical Investigation on Endogenous Biomarkers to Predict Strong OAT-Mediated Drug-Drug Interactions.

Correction to: Clinical Investigation on Endogenous Biomarkers to Predict Strong OAT-Mediated Drug-Drug Interactions.

Journal: Clinical pharmacokinetics
Published: February 17, 2022

"Can You Deny Her That?" Processes of Governmentality and Socialization of Parents in Elite Women's Gymnastics.

"Can You Deny Her That?" Processes of Governmentality and Socialization of Parents in Elite Women's Gymnastics.

Journal: Frontiers in psychology
Published: December 05, 2021

Prediction of the drug-drug interaction potential of the α1-acid glycoprotein bound, CYP3A4/CYP2C9 metabolized oncology drug, erdafitinib.

Prediction of the drug-drug interaction potential of the α1-acid glycoprotein bound, CYP3A4/CYP2C9 metabolized oncology drug, erdafitinib.

Journal: CPT: pharmacometrics & systems pharmacology
Published: February 26, 2021

Clinical Investigation on Endogenous Biomarkers to Predict Strong OAT-Mediated Drug-Drug Interactions.

Clinical Investigation on Endogenous Biomarkers to Predict Strong OAT-Mediated Drug-Drug Interactions.

Journal: Clinical pharmacokinetics
Published: February 10, 2021

Population pharmacokinetic modeling and simulation to support qualification of pyridoxic acid as endogenous biomarker of OAT1/3 renal transporters.

Population pharmacokinetic modeling and simulation to support qualification of pyridoxic acid as endogenous biomarker of OAT1/3 renal transporters.

Journal: CPT: pharmacometrics & systems pharmacology
Published: October 08, 2020

Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines.

Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines.

Journal: Nature communications
Published: January 12, 2020

Apalutamide Absorption, Metabolism, and Excretion in Healthy Men, and Enzyme Reaction in Human Hepatocytes.

Apalutamide Absorption, Metabolism, and Excretion in Healthy Men, and Enzyme Reaction in Human Hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: October 02, 2018
Showing 1-12 of 34

Last Updated: 09/26/2026