Frank-gerrit Klarner
Essen, NW 45141, Germany
Last Updated: 09/26/2026
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Found 41 publications
Allosteric Modulation of Pathological Ataxin-3 Aggregation: A Path to Spinocerebellar Ataxia Type-3 Therapies.
Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: February 05, 2025
Allosteric Modulation of Pathological Ataxin-3 Aggregation: A Path to Spinocerebellar Ataxia Type-3 Therapies.
Journal: bioRxiv : the preprint server for biology
Published: February 03, 2025
Anti-amyloid treatment is broadly effective in neuronopathic mucopolysaccharidoses and synergizes with gene therapy in MPS-IIIA.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: May 03, 2024
Characterization of Molecular Tweezer Binding on α-Synuclein with Native Top-Down Mass Spectrometry and Ion Mobility-Mass Spectrometry Reveals a Mechanism for Aggregation Inhibition.
Journal: Journal of the American Society for Mass Spectrometry
Published: November 07, 2023
The Amyloid Inhibitor CLR01 Relieves Autophagy and Ameliorates Neuropathology in a Severe Lysosomal Storage Disease.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: October 19, 2022
Correction for "Comparison of Three Amyloid Assembly Inhibitors: The Sugar scyllo-Inositol, the Polyphenol Epigallocatechin Gallate, and the Molecular Tweezer CLR01".
Journal: ACS chemical neuroscience
Published: August 24, 2022
Molecular Tweezers: Supramolecular Hosts with Broad-Spectrum Biological Applications.
Journal: Pharmacological reviews
Published: May 26, 2022
Advanced Molecular Tweezers with Lipid Anchors against SARS-CoV-2 and Other Respiratory Viruses.
Journal: JACS Au
Published: April 07, 2022
Correction to: The molecular tweezer CLR01 improves behavioral deficits and reduces tau pathology in P301S-tau transgenic mice.
Journal: Alzheimer's research & therapy
Published: April 23, 2021
Lysine-selective molecular tweezers are cell penetrant and concentrate in lysosomes.
Journal: Communications biology
Published: February 02, 2021
Inhibition of Staphylococcus aureus biofilm-forming functional amyloid by molecular tweezers.
Journal: Cell chemical biology
Published: October 16, 2020
The molecular tweezer CLR01 improves behavioral deficits and reduces tau pathology in P301S-tau transgenic mice.
Journal: Alzheimer's research & therapy
Published: September 25, 2020
Last Updated: 09/26/2026