Frank Karkossa - Publications

Towards a standard toolbox for compatibility testing of pediatric drug products: verification of standard vehicles for fruit juice, apple sauce, yogurt, and pudding through comparative biorelevant dissolution testing using pediatric furosemide mini-tablets.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Published: May 27, 2026

Comparative In Vitro Release Profiling of Brand and Generic Metoprolol Extended-Release Formulations in the Context of Product Switching.

Journal: Die Pharmazie

Published: December 19, 2025

Novel Strategies for the Formulation of Poorly Water-Soluble Drug Substances by Different Physical Modification Strategies with a Focus on Peroral Applications.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: June 02, 2025

What to consider for successful administration of oral liquids via enteral feeding tubes? a case study with paediatric ibuprofen suspensions.

Journal: International journal of pharmaceutics

Published: August 25, 2023

A systematic approach for assessing the suitability of enteral feeding tubes for the administration of controlled-release pellet formulations.

Journal: International journal of pharmaceutics

Published: July 18, 2021

A Biopredictive In Vitro Approach for Assessing Compatibility of a Novel Pediatric Hydrocortisone Drug Product within Common Pediatric Dosing Vehicles.

Journal: Pharmaceutical research

Published: April 09, 2020

Dissolution testing of modified release products with biorelevant media: An OrBiTo ring study using the USP apparatus III and IV.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Published: March 10, 2020

Individualized in vitro and in silico methods for predicting in vivo performance of enteric-coated tablets containing a narrow therapeutic index drug.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Published: August 27, 2018

A Biopredictive In Vitro Comparison of Oral Locally Acting Mesalazine Formulations by a Novel Dissolution Model for Assessing Intraluminal Drug Release in Individual Subjects.

Journal: Journal of pharmaceutical sciences

Published: January 05, 2018

Assessing the influence of media composition and ionic strength on drug release from commercial immediate-release and enteric-coated aspirin tablets.

Journal: The Journal of pharmacy and pharmacology

Published: February 28, 2017

Simulating Different Dosing Scenarios for a Child-Appropriate Valproate ER Formulation in a New Pediatric Two-Stage Dissolution Model.

Journal: AAPS PharmSciTech

Published: October 10, 2016