Frank Sicheri
Toronto, ON M5S1A8, Canada
Last Updated: 09/26/2026
Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 102 publications
Structural Transformation of a BRAF Inhibitor into a Selective PKR Inhibitor.
Journal: Journal of medicinal chemistry
Published: June 22, 2026
A Chemical-Genetic Interaction Matrix Reveals Drug Mechanism and Genetic Architecture.
Journal: bioRxiv : the preprint server for biology
Published: February 09, 2026
Discovery and development of potent and selective dual NUAK/MARK inhibitors as Hippo pathway modulators for the treatment of cancer.
Journal: European journal of medicinal chemistry
Published: January 27, 2026
Structure and mechanism of inhibition of lysine demethylase 2A (KDM2A) by compound 183c.
Journal: Communications chemistry
Published: December 17, 2025
Molecular basis for the activation of Aurora A and Plk1 kinases during mitotic entry.
Journal: The EMBO journal
Published: November 03, 2025
Design of a Targeted Covalent Probe to Interrogate the DNA Polymerase Activity of Polθ.
Journal: ACS medicinal chemistry letters
Published: October 25, 2025
The Discovery of RP-2119: A Potent, Selective, and Orally Bioavailable Polθ ATPase Inhibitor.
Journal: Journal of medicinal chemistry
Published: September 08, 2025
Author Correction: Structures of KEOPS bound to tRNA reveal functional roles of the kinase Bud32.
Journal: Nature communications
Published: July 24, 2025
Analysis of Fbox substrate adapter proteins using ProteoSync, a program for projection of evolutionary conservation onto protein atomic coordinates.
Journal: Computational and structural biotechnology journal
Published: June 15, 2025
Author Correction: A substrate binding model for the KEOPS tRNA modifying complex.
Journal: Nature communications
Published: May 22, 2025
The molecular glue CLEO4-88 inhibits the ACAA1 thiolase by induced binding to GID4.
Journal: Nature chemical biology
Published: May 19, 2025
Last Updated: 09/26/2026