Frank Wempe

Frankfurt Am Main, HE 60590, Germany

Last Updated: 09/26/2026

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Found 11 publications

Endogenous protein tagging coupled with a CRISPR screening approach identifies UBE3C as a potential MYC oncogene regulator.

Endogenous protein tagging coupled with a CRISPR screening approach identifies UBE3C as a potential MYC oncogene regulator.

Journal: Scientific reports
Published: June 24, 2025

The MYC-Regulated RNA-Binding Proteins hnRNPC and LARP1 Are Drivers of Multiple Myeloma Cell Growth and Disease Progression and Negatively Predict Patient Survival.

The MYC-Regulated RNA-Binding Proteins hnRNPC and LARP1 Are Drivers of Multiple Myeloma Cell Growth and Disease Progression and Negatively Predict Patient Survival.

Journal: Cancers
Published: October 05, 2023

Correction: Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia.

Correction: Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia.

Journal: Leukemia
Published: November 08, 2022

Selection-free endogenous tagging of cell lines by bicistronic co-expression of the surface antigen NGFR.

Selection-free endogenous tagging of cell lines by bicistronic co-expression of the surface antigen NGFR.

Journal: MethodsX
Published: September 16, 2022

Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia.

Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia.

Journal: Leukemia
Published: December 06, 2021

Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target Gene.

Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target Gene.

Journal: Cells
Published: October 30, 2021

Role of LTBP4 in alveolarization, angiogenesis, and fibrosis in lungs.

Role of LTBP4 in alveolarization, angiogenesis, and fibrosis in lungs.

Journal: American journal of physiology. Lung cellular and molecular physiology
Published: January 26, 2017

Ltbp4 regulates Pdgfrβ expression via TGFβ-dependent modulation of Nrf2 transcription factor function.

Ltbp4 regulates Pdgfrβ expression via TGFβ-dependent modulation of Nrf2 transcription factor function.

Journal: Matrix biology : journal of the International Society for Matrix Biology
Published: July 29, 2016

Cytochrome P450 enzymes but not NADPH oxidases are the source of the NADPH-dependent lucigenin chemiluminescence in membrane assays.

Cytochrome P450 enzymes but not NADPH oxidases are the source of the NADPH-dependent lucigenin chemiluminescence in membrane assays.

Journal: Free radical biology & medicine
Published: July 14, 2016

Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms.

Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms.

Journal: Disease models & mechanisms
Published: October 30, 2014

Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD.

Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD.

Journal: Disease models & mechanisms
Published: September 19, 2013
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Last Updated: 09/26/2026