Franz Bracher
Munich, BY 80336, Germany
Last Updated: 09/26/2026
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Found 153 publications
TPC1-dependent control of endosomal pH and transferrin uptake determines cellular iron status.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: August 05, 2026
Inhibition of endolysosomal two-pore channel 2 (TPC2) induces osteoblast differentiation and matrix mineralization while targeting autophagy.
Journal: Journal of endocrinological investigation
Published: October 21, 2025
Lead Structure-Based Hybridization Strategy Reveals Major Potency Enhancement of SirReal-Type Sirt2 Inhibitors.
Journal: International journal of molecular sciences
Published: September 03, 2025
Balsalazide-Derived Heterotriaryls as Sirtuin 5 Inhibitors: A Case Study of a Reversible Covalent Inhibition Strategy.
Journal: Molecules (Basel, Switzerland)
Published: August 22, 2025
O-linked glycan-dependent gating of TPC2 controls lysosomal excitability and organelle remodeling.
Journal: Nature communications
Published: August 07, 2025
TRPML1 suppresses pulmonary fibrosis by limiting collagen and elastin deposition.
Journal: The EMBO journal
Published: July 14, 2025
Synthetic Analogs of the Alkaloid Cassiarin A with Enhanced Antimalarial Activity.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: June 05, 2025
TRPML2 channel modulation by PI(3,5)P₂ and small-molecule agonists controls endosomal vesicle dynamics.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: May 22, 2025
Serendipitous and Systematic Chemoproteomic Discovery of MBLAC2, HINT1, and NME1-4 Inhibitors from Histone Deacetylase-Targeting Pharmacophores.
Journal: ACS chemical biology
Published: May 09, 2025
Single-cell spatial transcriptomic profiling defines a pathogenic inflammatory niche in chronic active multiple sclerosis lesions.
Journal: Immunity
Published: April 16, 2025
Last Updated: 09/26/2026