Fraser Soares

Toronto, ON, Canada

Last Updated: 09/26/2026

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Found 30 publications

Allogeneic DNT cell therapy synergizes with T cells to promote anti-leukemic activities while suppressing GvHD.

Allogeneic DNT cell therapy synergizes with T cells to promote anti-leukemic activities while suppressing GvHD.

Journal: Journal of experimental & clinical cancer research : CR
Published: August 28, 2024

In vivo CRISPR screens identify a dual function of MEN1 in regulating tumor-microenvironment interactions.

In vivo CRISPR screens identify a dual function of MEN1 in regulating tumor-microenvironment interactions.

Journal: Nature genetics
Published: November 10, 2023

Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways.

Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways.

Journal: Nature communications
Published: March 01, 2023

MYC reshapes CTCF-mediated chromatin architecture in prostate cancer.

MYC reshapes CTCF-mediated chromatin architecture in prostate cancer.

Journal: Nature communications
Published: July 10, 2022

Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.

Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.

Journal: Nucleic acids research
Published: May 31, 2022

The Basis and Promise of Programmable RNA Editing and Modification.

The Basis and Promise of Programmable RNA Editing and Modification.

Journal: Frontiers in genetics
Published: December 13, 2021

Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1.

Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1.

Journal: Molecular cell
Published: June 04, 2021

N6-Methyladenosine Reader YTHDF1 Promotes ARHGEF2 Translation and RhoA Signaling in Colorectal Cancer.

N6-Methyladenosine Reader YTHDF1 Promotes ARHGEF2 Translation and RhoA Signaling in Colorectal Cancer.

Journal: Gastroenterology
Published: May 17, 2021

CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer.

CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer.

Journal: Oncogene
Published: November 03, 2020

Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression.

Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression.

Journal: Nature cell biology
Published: September 15, 2020

CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer.

CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer.

Journal: Nature communications
Published: May 20, 2020

RNA N6-Methyladenosine Methyltransferase METTL3 Facilitates Colorectal Cancer by Activating the m6A-GLUT1-mTORC1 Axis and Is a Therapeutic Target.

RNA N6-Methyladenosine Methyltransferase METTL3 Facilitates Colorectal Cancer by Activating the m6A-GLUT1-mTORC1 Axis and Is a Therapeutic Target.

Journal: Gastroenterology
Published: April 26, 2020
Showing 1-12 of 30

Last Updated: 09/26/2026