Frauke Assmus

Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 15 publications

Pharmacokinetics, safety, and tolerability of an oxfendazole tablet formulation: a phase 1, randomized, placebo-controlled trial in healthy African volunteers.

Pharmacokinetics, safety, and tolerability of an oxfendazole tablet formulation: a phase 1, randomized, placebo-controlled trial in healthy African volunteers.

Journal: Antimicrobial agents and chemotherapy

Published: February 18, 2026

Population pharmacokinetics of DNDI-6148 in healthy adults.

Population pharmacokinetics of DNDI-6148 in healthy adults.

Journal: PLoS neglected tropical diseases

Published: November 03, 2025

Repurposing Oxfendazole for Onchocerciasis: Population Pharmacokinetics of a Tablet Formulation in Healthy African Adults.

Repurposing Oxfendazole for Onchocerciasis: Population Pharmacokinetics of a Tablet Formulation in Healthy African Adults.

Journal: CPT: pharmacometrics & systems pharmacology

Published: September 25, 2025

Population pharmacokinetic-pharmacodynamic analysis of benznidazole monotherapy and combination therapy with fosravuconazole in chronic Chagas disease (BENDITA).

Population pharmacokinetic-pharmacodynamic analysis of benznidazole monotherapy and combination therapy with fosravuconazole in chronic Chagas disease (BENDITA).

Journal: PLoS neglected tropical diseases

Published: April 15, 2025

Safety, tolerability and pharmacokinetics of DNDI-6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants.

Safety, tolerability and pharmacokinetics of DNDI-6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants.

Journal: British journal of clinical pharmacology

Published: April 04, 2025

Pharmacokinetic-pharmacodynamic modeling of benznidazole and its antitrypanosomal activity in a murine model of chronic Chagas disease.

Pharmacokinetic-pharmacodynamic modeling of benznidazole and its antitrypanosomal activity in a murine model of chronic Chagas disease.

Journal: PLoS neglected tropical diseases

Published: September 24, 2024

Quantifying anti-trypanosomal treatment effects in chronic indeterminate Chagas disease: a secondary analysis of individual patient data from two proof-of-concept trials.

Quantifying anti-trypanosomal treatment effects in chronic indeterminate Chagas disease: a secondary analysis of individual patient data from two proof-of-concept trials.

Journal: The Lancet. Microbe

Published: July 18, 2024

Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19.

Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19.

Journal: Microorganisms

Published: July 07, 2022

Drug development for the treatment of onchocerciasis: Population pharmacokinetic and adverse events modeling of emodepside.

Drug development for the treatment of onchocerciasis: Population pharmacokinetic and adverse events modeling of emodepside.

Journal: PLoS neglected tropical diseases

Published: September 07, 2021

Incorporation of lysosomal sequestration in the mechanistic model for prediction of tissue distribution of basic drugs.

Incorporation of lysosomal sequestration in the mechanistic model for prediction of tissue distribution of basic drugs.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: April 27, 2017

In Vitro and in Silico Tools To Assess Extent of Cellular Uptake and Lysosomal Sequestration of Respiratory Drugs in Human Alveolar Macrophages.

In Vitro and in Silico Tools To Assess Extent of Cellular Uptake and Lysosomal Sequestration of Respiratory Drugs in Human Alveolar Macrophages.

Journal: Molecular pharmaceutics

Published: March 03, 2017

31P and 1H NMR Studies of the Molecular Organization of Lipids in the Parallel Artificial Membrane Permeability Assay.

31P and 1H NMR Studies of the Molecular Organization of Lipids in the Parallel Artificial Membrane Permeability Assay.

Journal: Molecular pharmaceutics

Published: December 16, 2016

Showing 1-12 of 15

Last Updated: 09/26/2026