Frauke Christ

Leuven, VLG, Belgium

Last Updated: 09/26/2026

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Found 88 publications

The LEDGIN GS-9822 inhibits HIV-2 infection and enhances HIV-2 latency.

The LEDGIN GS-9822 inhibits HIV-2 infection and enhances HIV-2 latency.

Journal: Microbiology spectrum

Published: April 27, 2026

Role of LEDGF/p75 (PSIP1) in oncogenesis. Insights in molecular mechanism and therapeutic potential.

Role of LEDGF/p75 (PSIP1) in oncogenesis. Insights in molecular mechanism and therapeutic potential.

Journal: Biochimica et biophysica acta. Reviews on cancer

Published: October 01, 2024

Rational fragment-based design of compounds targeting the PWWP domain of the HRP family.

Rational fragment-based design of compounds targeting the PWWP domain of the HRP family.

Journal: European journal of medicinal chemistry

Published: July 29, 2024

LEDGF interacts with the NID domain of MeCP2 and modulates MeCP2 condensates.

LEDGF interacts with the NID domain of MeCP2 and modulates MeCP2 condensates.

Journal: Structure (London, England : 1993)

Published: June 02, 2024

BRD4 modulator ZL0580 and LEDGINs additively block and lock HIV-1 transcription.

BRD4 modulator ZL0580 and LEDGINs additively block and lock HIV-1 transcription.

Journal: Nature communications

Published: April 08, 2024

The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function.

The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function.

Journal: Cells

Published: November 24, 2023

Pharmacological advances in anti-retroviral therapy for human immunodeficiency virus-1 infection: A comprehensive review.

Pharmacological advances in anti-retroviral therapy for human immunodeficiency virus-1 infection: A comprehensive review.

Journal: Reviews in medical virology

Published: November 13, 2023

Determinants of Retroviral Integration and Implications for Gene Therapeutic MLV-Based Vectors and for a Cure for HIV-1 Infection.

Determinants of Retroviral Integration and Implications for Gene Therapeutic MLV-Based Vectors and for a Cure for HIV-1 Infection.

Journal: Viruses

Published: November 30, 2022

BET-Independent Murine Leukemia Virus Integration Is Retargeted In Vivo and Selects Distinct Genomic Elements for Lymphomagenesis.

BET-Independent Murine Leukemia Virus Integration Is Retargeted In Vivo and Selects Distinct Genomic Elements for Lymphomagenesis.

Journal: Microbiology spectrum

Published: July 19, 2022

Design, synthesis, in silico studies, and antiproliferative evaluations of novel indolin-2-one derivatives containing 3-hydroxy-4-pyridinone fragment.

Design, synthesis, in silico studies, and antiproliferative evaluations of novel indolin-2-one derivatives containing 3-hydroxy-4-pyridinone fragment.

Journal: Bioorganic & medicinal chemistry letters

Published: February 06, 2022

Novel CFTR modulator combinations maximise rescue of G85E and N1303K in rectal organoids.

Novel CFTR modulator combinations maximise rescue of G85E and N1303K in rectal organoids.

Journal: ERJ open research

Published: December 22, 2021

CRISPR/Cas9-Induced Mutagenesis Corroborates the Role of Transportin-SR2 in HIV-1 Nuclear Import.

CRISPR/Cas9-Induced Mutagenesis Corroborates the Role of Transportin-SR2 in HIV-1 Nuclear Import.

Journal: Microbiology spectrum

Published: October 06, 2021

Showing 1-12 of 88

Last Updated: 09/26/2026