Frederick A. Mallette

Succ. Centre Ville
Montreal, QC, Canada

Last Updated: 09/26/2026

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Found 47 publications

SMOC2 promotes partial epithelial-to-mesenchymal transition and maladaptive repair in renal tubular epithelial cells.

SMOC2 promotes partial epithelial-to-mesenchymal transition and maladaptive repair in renal tubular epithelial cells.

Journal: JCI insight
Published: August 12, 2026

BH3 mimetic therapies for CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia.

BH3 mimetic therapies for CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia.

Journal: Trends in molecular medicine
Published: May 07, 2025

Inhibition of MCL-1 to eliminate senescent cells and mitigate renal fibrosis in aristolochic acid nephropathy.

Inhibition of MCL-1 to eliminate senescent cells and mitigate renal fibrosis in aristolochic acid nephropathy.

Journal: Cell death & disease
Published: February 27, 2025

Unbiased analysis of NUP98-KDM5A-induced murine leukemia reveals phenotypic heterogeneity recapitulating human disease subtypes.

Unbiased analysis of NUP98-KDM5A-induced murine leukemia reveals phenotypic heterogeneity recapitulating human disease subtypes.

Journal: Experimental hematology
Published: September 18, 2024

R-2-hydroxyglutarate-mediated inhibition of KDM4A compromises telomere integrity.

R-2-hydroxyglutarate-mediated inhibition of KDM4A compromises telomere integrity.

Journal: Nucleic acids research
Published: August 23, 2024

O-GlcNAcylation of FOXK1 co-opts BAP1 to orchestrate the E2F pathway and promotes oncogenesis.

O-GlcNAcylation of FOXK1 co-opts BAP1 to orchestrate the E2F pathway and promotes oncogenesis.

Journal: Nature communications
Published: January 29, 2024

Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions.

Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions.

Journal: The journals of gerontology. Series A, Biological sciences and medical sciences
Published: January 03, 2024

FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair.

FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair.

Journal: Science advances
Published: August 09, 2023

An inventory of crosstalk between ubiquitination and other post-translational modifications in orchestrating cellular processes.

An inventory of crosstalk between ubiquitination and other post-translational modifications in orchestrating cellular processes.

Journal: iScience
Published: May 11, 2023

CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax.

CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax.

Journal: Cell reports
Published: February 09, 2023

Obesity triggers tumoral senescence and renders poorly immunogenic malignancies amenable to senolysis.

Obesity triggers tumoral senescence and renders poorly immunogenic malignancies amenable to senolysis.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: December 27, 2022

Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results.

Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results.

Journal: Nature medicine
Published: December 27, 2022
Showing 1-12 of 47

Last Updated: 09/26/2026