Fredrik J. Ekstrom

Umea, AC, Sweden

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 27 publications

Analysis of ligand recognition by choline O-acetyltransferase reveals thiol-reactive assay interference and weak ligand affinity in solution.

Analysis of ligand recognition by choline O-acetyltransferase reveals thiol-reactive assay interference and weak ligand affinity in solution.

Journal: The Journal of biological chemistry

Published: January 19, 2026

Establishment of a real-time monitored animal model to evaluate novel therapeutic strategies for organophosphorus nerve agent poisonings.

Establishment of a real-time monitored animal model to evaluate novel therapeutic strategies for organophosphorus nerve agent poisonings.

Journal: Toxicology and applied pharmacology

Published: November 21, 2025

Potent and selective indole-based inhibitors targeting disease-transmitting mosquitoes.

Potent and selective indole-based inhibitors targeting disease-transmitting mosquitoes.

Journal: RSC medicinal chemistry

Published: September 10, 2025

The Molecular Properties of Honey Bee Acetylcholinesterase Reveal Opportunities to Avoid Off-Target Effects in Insecticide Discovery.

The Molecular Properties of Honey Bee Acetylcholinesterase Reveal Opportunities to Avoid Off-Target Effects in Insecticide Discovery.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: February 20, 2025

Enzyme Dynamics Determine the Potency and Selectivity of Inhibitors Targeting Disease-Transmitting Mosquitoes.

Enzyme Dynamics Determine the Potency and Selectivity of Inhibitors Targeting Disease-Transmitting Mosquitoes.

Journal: ACS infectious diseases

Published: September 18, 2024

Structure-Activity Relationships Reveal Beneficial Selectivity Profiles of Inhibitors Targeting Acetylcholinesterase of Disease-Transmitting Mosquitoes.

Structure-Activity Relationships Reveal Beneficial Selectivity Profiles of Inhibitors Targeting Acetylcholinesterase of Disease-Transmitting Mosquitoes.

Journal: Journal of medicinal chemistry

Published: April 24, 2023

Broad-Spectrum Antidote Discovery by Untangling the Reactivation Mechanism of Nerve-Agent-Inhibited Acetylcholinesterase.

Broad-Spectrum Antidote Discovery by Untangling the Reactivation Mechanism of Nerve-Agent-Inhibited Acetylcholinesterase.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: March 02, 2022

Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures.

Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures.

Journal: ACS medicinal chemistry letters

Published: January 03, 2022

In Situ Assembly of Choline Acetyltransferase Ligands by a Hydrothiolation Reaction Reveals Key Determinants for Inhibitor Design.

In Situ Assembly of Choline Acetyltransferase Ligands by a Hydrothiolation Reaction Reveals Key Determinants for Inhibitor Design.

Journal: Angewandte Chemie (International ed. in English)

Published: September 02, 2020

Physical Mechanisms Governing Substituent Effects on Arene-Arene Interactions in a Protein Milieu.

Physical Mechanisms Governing Substituent Effects on Arene-Arene Interactions in a Protein Milieu.

Journal: The journal of physical chemistry. B

Published: July 02, 2020

Noncovalent Inhibitors of Mosquito Acetylcholinesterase 1 with Resistance-Breaking Potency.

Noncovalent Inhibitors of Mosquito Acetylcholinesterase 1 with Resistance-Breaking Potency.

Journal: Journal of medicinal chemistry

Published: October 20, 2018

Influence of Enantiomeric Inhibitors on the Dynamics of Acetylcholinesterase Measured by Elastic Incoherent Neutron Scattering.

Influence of Enantiomeric Inhibitors on the Dynamics of Acetylcholinesterase Measured by Elastic Incoherent Neutron Scattering.

Journal: The journal of physical chemistry. B

Published: August 16, 2018

Showing 1-12 of 27

Last Updated: 09/26/2026