Friederike Gieseke
Mainz, RP 55131, Germany
Last Updated: 09/26/2026
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Found 14 publications
A hexamerization-enhanced, Fc-silenced agonistic CD27 antibody amplifies T-cell effector functions as single agent and in combination with PD-1 blockade.
Journal: Scientific reports
Published: March 20, 2025
DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.
Journal: Journal for immunotherapy of cancer
Published: April 26, 2022
An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation.
Journal: Oncoimmunology
Published: February 21, 2022
Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors.
Journal: Cancer discovery
Published: October 18, 2021
Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models.
Journal: Science translational medicine
Published: September 13, 2021
Long-Term Follow-Up After the Application of Mesenchymal Stromal Cells in Children and Adolescents with Steroid-Refractory Graft-Versus-Host Disease.
Journal: Stem cells and development
Published: January 15, 2021
Duokines: a novel class of dual-acting co-stimulatory molecules acting in cis or trans.
Journal: Oncoimmunology
Published: March 22, 2018
Enzymatic characterization of novel arylsulfatase A variants using human arylsulfatase A-deficient immortalized mesenchymal stromal cells.
Journal: Human mutation
Published: February 17, 2017
Donor choice in haploidentical stem cell transplantation: fetal microchimerism is associated with better outcome in pediatric leukemia patients.
Journal: Bone marrow transplantation
Published: June 23, 2015
The PML domain of PML-RARα blocks senescence to promote leukemia.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: August 06, 2014
Human leukocyte antigen DR surface expression on CD14+ monocytes during adverse events after hematopoietic stem cell transplantation.
Journal: Annals of hematology
Published: June 02, 2014
Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in a CD44-dependent fashion.
Journal: Journal of hepatology
Published: January 15, 2013
Last Updated: 09/26/2026