G G. Kucukguzel

Istanbul, Turkey

Last Updated: 09/26/2026

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Found 39 publications

2-Pyrazoline-5-One Derivative Suppresses Cell Proliferation and Induces Apoptosis With Upregulation of Bax in Breast Cancer Cells.

2-Pyrazoline-5-One Derivative Suppresses Cell Proliferation and Induces Apoptosis With Upregulation of Bax in Breast Cancer Cells.

Journal: Journal of biochemical and molecular toxicology

Published: April 13, 2026

Ibuprofen and nimesulide derivatives selectively induce apoptosis in HER2-positive breast cancer via inhibition of the PLA₂-COX-2-NF-κB pathway.

Ibuprofen and nimesulide derivatives selectively induce apoptosis in HER2-positive breast cancer via inhibition of the PLA₂-COX-2-NF-κB pathway.

Journal: Molecular biology reports

Published: December 01, 2025

Synthesis, characterization, biological evaluation, and molecular modeling of novel nimesulide urea derivatives as potential MetAP2 inhibitors.

Synthesis, characterization, biological evaluation, and molecular modeling of novel nimesulide urea derivatives as potential MetAP2 inhibitors.

Journal: Scientific reports

Published: November 18, 2025

Novel hydrazide-hydrazone derivatives containing flurbiprofen 1,2,4-triazole as anticancer agents: design, synthesis and biological evaluation.

Novel hydrazide-hydrazone derivatives containing flurbiprofen 1,2,4-triazole as anticancer agents: design, synthesis and biological evaluation.

Journal: Acta chimica Slovenica

Published: August 08, 2025

Investigation of novel nimesulide derivatives against breast cancer.

Investigation of novel nimesulide derivatives against breast cancer.

Journal: Bioorganic chemistry

Published: April 15, 2025

Design and synthesis of thiosemicarbazides and 1,2,4-triazoles derived from ibuprofen as potential MetAP (type II) inhibitors.

Design and synthesis of thiosemicarbazides and 1,2,4-triazoles derived from ibuprofen as potential MetAP (type II) inhibitors.

Journal: Chemico-biological interactions

Published: February 05, 2025

A Novel PEtOx-Based Nanogel Targeting Prostate Cancer Cells for Drug Delivery.

A Novel PEtOx-Based Nanogel Targeting Prostate Cancer Cells for Drug Delivery.

Journal: Macromolecular bioscience

Published: July 12, 2023

Synthesis and Evaluation of Novel Metacetamol Derivatives with Hydrazone Moiety as Anticancer and Antimicrobial Agents.

Synthesis and Evaluation of Novel Metacetamol Derivatives with Hydrazone Moiety as Anticancer and Antimicrobial Agents.

Journal: Chemistry & biodiversity

Published: May 25, 2023

Synthesis, antimicrobial properties and in silico studies of aryloxyacetic acid derivatives with hydrazone or thiazolidine-4-one scaffold.

Synthesis, antimicrobial properties and in silico studies of aryloxyacetic acid derivatives with hydrazone or thiazolidine-4-one scaffold.

Journal: Journal of biomolecular structure & dynamics

Published: September 14, 2022

Synthesis, Antimicrobial Evaluation, and Molecular Modeling Studies of New Thiosemicarbazide-Triazole Hybrid Derivatives of (S)-Naproxen.

Synthesis, Antimicrobial Evaluation, and Molecular Modeling Studies of New Thiosemicarbazide-Triazole Hybrid Derivatives of (S)-Naproxen.

Journal: Chemistry & biodiversity

Published: November 08, 2021

Thioethers: An Overview.

Thioethers: An Overview.

Journal: Current drug targets

Published: January 30, 2021

Design and synthesis of novel (S)-Naproxen hydrazide-hydrazones as potent VEGFR-2 inhibitors and their evaluation in vitro/in vivo breast cancer models.

Design and synthesis of novel (S)-Naproxen hydrazide-hydrazones as potent VEGFR-2 inhibitors and their evaluation in vitro/in vivo breast cancer models.

Journal: Bioorganic & medicinal chemistry

Published: December 28, 2020

Showing 1-12 of 39

Last Updated: 09/26/2026