Gabriella Leonarduzzi

Turin, Italy

Last Updated: 09/26/2026

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Found 38 publications

Elevated 24-hydroxycholesterol levels counteract okadaic acid-induced tau hyperphosphorylation and neuronal morphology impairment.

Elevated 24-hydroxycholesterol levels counteract okadaic acid-induced tau hyperphosphorylation and neuronal morphology impairment.

Journal: Neurobiology of disease

Published: February 27, 2025

The Emerging Role of PCSK9 in the Pathogenesis of Alzheimer's Disease: A Possible Target for the Disease Treatment.

The Emerging Role of PCSK9 in the Pathogenesis of Alzheimer's Disease: A Possible Target for the Disease Treatment.

Journal: International journal of molecular sciences

Published: November 25, 2024

Altered Brain Cholesterol Machinery in a Down Syndrome Mouse Model: A Possible Common Feature with Alzheimer's Disease.

Altered Brain Cholesterol Machinery in a Down Syndrome Mouse Model: A Possible Common Feature with Alzheimer's Disease.

Journal: Antioxidants (Basel, Switzerland)

Published: March 06, 2024

24-Hydroxycholesterol Induces Tau Proteasome-Dependent Degradation via the SIRT1/PGC1α/Nrf2 Pathway: A Potential Mechanism to Counteract Alzheimer's Disease.

24-Hydroxycholesterol Induces Tau Proteasome-Dependent Degradation via the SIRT1/PGC1α/Nrf2 Pathway: A Potential Mechanism to Counteract Alzheimer's Disease.

Journal: Antioxidants (Basel, Switzerland)

Published: February 03, 2023

ApoE3 vs. ApoE4 Astrocytes: A Detailed Analysis Provides New Insights into Differences in Cholesterol Homeostasis.

ApoE3 vs. ApoE4 Astrocytes: A Detailed Analysis Provides New Insights into Differences in Cholesterol Homeostasis.

Journal: Antioxidants (Basel, Switzerland)

Published: October 12, 2022

Macrophage polarization by potential nutraceutical compounds: A strategic approach to counteract inflammation in atherosclerosis.

Macrophage polarization by potential nutraceutical compounds: A strategic approach to counteract inflammation in atherosclerosis.

Journal: Free radical biology & medicine

Published: December 02, 2021

Cholesterol Dysmetabolism in Alzheimer's Disease: A Starring Role for Astrocytes?

Cholesterol Dysmetabolism in Alzheimer's Disease: A Starring Role for Astrocytes?

Journal: Antioxidants (Basel, Switzerland)

Published: November 02, 2021

The Controversial Role of 24-S-Hydroxycholesterol in Alzheimer's Disease.

The Controversial Role of 24-S-Hydroxycholesterol in Alzheimer's Disease.

Journal: Antioxidants (Basel, Switzerland)

Published: April 14, 2021

Up-regulation of PCSK6 by lipid oxidation products: A possible role in atherosclerosis.

Up-regulation of PCSK6 by lipid oxidation products: A possible role in atherosclerosis.

Journal: Biochimie

Published: October 20, 2020

Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2.

Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2.

Journal: Redox biology

Published: September 04, 2020

A Crosstalk Between Brain Cholesterol Oxidation and Glucose Metabolism in Alzheimer's Disease.

A Crosstalk Between Brain Cholesterol Oxidation and Glucose Metabolism in Alzheimer's Disease.

Journal: Frontiers in neuroscience

Published: April 05, 2019

Up-regulation of COX-2 and mPGES-1 by 27-hydroxycholesterol and 4-hydroxynonenal: A crucial role in atherosclerotic plaque instability.

Up-regulation of COX-2 and mPGES-1 by 27-hydroxycholesterol and 4-hydroxynonenal: A crucial role in atherosclerotic plaque instability.

Journal: Free radical biology & medicine

Published: June 05, 2018

Showing 1-12 of 38

Last Updated: 09/26/2026