Last Updated: 09/26/2026
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Found 10 publications
A first-in-human phase 1 clinical study in healthy volunteers to assess the safety, tolerability and pharmacokinetics of EDI048, a novel promising agent to treat enteric cryptosporidiosis.
Journal: The Journal of infectious diseases
Published: February 02, 2026
Concentration-QTcF Modeling of Icenticaftor from a Randomized, Placebo- and Positive-Controlled Thorough QT Study in Healthy Participants.
Journal: Clinical pharmacology in drug development
Published: October 17, 2023
Effects of triclabendazole and its metabolite exposure on the heart-rate-corrected QT intervals: A randomized, placebo- and positive-controlled thorough QT study in healthy individuals.
Journal: Clinical and translational science
Published: April 09, 2023
Evaluation of a Low-Fat Low-Calorie Meal on the Relative Bioavailability of Trametinib and Dabrafenib: Results From a Randomized, Open-Label, 2-Part Study in Healthy Participants.
Journal: Clinical pharmacology in drug development
Published: August 08, 2022
Discovery and Optimization of Pyrazole Amides as Inhibitors of ELOVL1.
Journal: Journal of medicinal chemistry
Published: November 08, 2021
Models and Approaches Describing the Metabolism, Transport, and Toxicity of Drugs Administered by the Ocular Route.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: June 11, 2018
Pharmacokinetics and safety of olopatadine hydrochloride 0.77% in healthy subjects with asymptomatic eyes: data from 2 independent clinical studies.
Journal: Clinical ophthalmology (Auckland, N.Z.)
Published: April 25, 2017
Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles.
Journal: Journal of medicinal chemistry
Published: July 02, 2016
Ocular pharmacokinetics comparison between 0.2% olopatadine and 0.77% olopatadine hydrochloride ophthalmic solutions administered to male New Zealand white rabbits.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Published: March 17, 2015
A Novel Study Using Accelerated Mass Spectrometry to Evaluate the Pharmacokinetics of Total (14)C AL-8309 (Tandospirone) Following Topical Ocular Administration in Healthy Male Subjects.
Journal: Clinical pharmacology in drug development
Published: January 01, 2012
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Last Updated: 09/26/2026